Comparison of procalcitonin and CrP in the postoperative course after lung decortication

Carboni, Giovanni L; Fahrner, Rene; Gazdhar, Amiq; Printzen, Gert; Schmid, Ralph Alexander; Hoksch, Beatrix (2008). Comparison of procalcitonin and CrP in the postoperative course after lung decortication. European journal of cardio-thoracic surgery, 33(5), pp. 777-80. Oxford: Elsevier Science B.V. 10.1016/j.ejcts.2008.02.013

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OBJECTIVE: The objective of this prospective study was to compare the clinical value of procalcitonin (PCT) and C-reactive protein (CrP) plasma concentrations in their postoperative course after decortication. METHODS: Twenty-two patients requiring surgery for pleural empyema were chosen for this prospective study. Routine blood samples including CrP and PCT plasma concentrations were taken before the operation and on the 1st, 2nd, 3rd, and 7th postoperative day. RESULTS: Due to infection PCT and CrP were elevated preoperatively. In the postoperative course both PCT and CrP reached peak-levels on day 2 with values up to 43.55 ng/ml and 384.00 mg/l, respectively. In PCT the rise was followed by a clear decrease in 20 (90.9 %) patients until day 7. In contrast the CrP levels decreased slowly and only seven (54.5%) patients had values of 100 mg/l or below on day 7. PCT showed a better correlation with the clinic in case of septic course than CrP does. CONCLUSIONS: PCT reflects postoperative clinical course more accurately than CrP. Therefore, PCT is a more appropriate laboratory parameter to monitor patients after surgery for pleural empyema.

Item Type:

Journal Article (Original Article)

Division/Institute:

04 Faculty of Medicine > Department of Gastro-intestinal, Liver and Lung Disorders (DMLL) > Clinic of Thoracic Surgery
04 Faculty of Medicine > Department of Haematology, Oncology, Infectious Diseases, Laboratory Medicine and Hospital Pharmacy (DOLS) > Institute of Clinical Chemistry

UniBE Contributor:

Carboni, Giovanni Luca; Printzen, Gert; Schmid, Ralph and Hoksch, Beatrix

ISSN:

1010-7940

ISBN:

18374593

Publisher:

Elsevier Science B.V.

Language:

English

Submitter:

Factscience Import

Date Deposited:

04 Oct 2013 15:05

Last Modified:

29 Oct 2019 00:31

Publisher DOI:

10.1016/j.ejcts.2008.02.013

PubMed ID:

18374593

Web of Science ID:

000256149600005

BORIS DOI:

10.7892/boris.28110

URI:

https://boris.unibe.ch/id/eprint/28110 (FactScience: 116811)

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