The lectin-like domain of tumor necrosis factor improves lung function after rat lung transplantation--potential role for a reduction in reactive oxygen species generation

Hamacher, Jürg; Stammberger, Uz; Roux, Jeremie; Kumar, Sanjiv; Yang, Guang; Xiong, Chenling; Schmid, Ralph A; Fakin, Richard M; Chakraborty, Trinad; Hossain, Hamid M D; Pittet, Jean-François; Wendel, Albrecht; Black, Stephen M; Lucas, Rudolf (2010). The lectin-like domain of tumor necrosis factor improves lung function after rat lung transplantation--potential role for a reduction in reactive oxygen species generation. Critical care medicine, 38(3), pp. 871-8. Baltimore, Md.: Lippincott Williams & Wilkins 10.1097/CCM.0b013e3181cdf725

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To test the hypothesis that the lectin-like domain of tumor necrosis factor, mimicked by the TIP peptide, can improve lung function after unilateral orthotopic lung isotransplantation. Because of a lack of a specific treatment for ischemia reperfusion-mediated lung injury, accompanied by a disrupted barrier integrity and a dysfunctional alveolar liquid clearance, alternative therapies restoring these parameters after lung transplantation are required.

Item Type:

Journal Article (Original Article)

Division/Institute:

04 Faculty of Medicine > Department of Gastro-intestinal, Liver and Lung Disorders (DMLL) > Clinic of Thoracic Surgery

UniBE Contributor:

Schmid, Ralph

ISSN:

0090-3493

Publisher:

Lippincott Williams & Wilkins

Language:

English

Submitter:

Factscience Import

Date Deposited:

04 Oct 2013 14:07

Last Modified:

04 May 2014 23:04

Publisher DOI:

10.1097/CCM.0b013e3181cdf725

PubMed ID:

20081530

Web of Science ID:

000275266200019

URI:

https://boris.unibe.ch/id/eprint/282 (FactScience: 197301)

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