Simultaneous, bilateral anterior ischemic optic neuropathy (AION) in polycythemia vera: a case report

Tönz, M S; Rigamonti, V; Iliev, M E (2008). Simultaneous, bilateral anterior ischemic optic neuropathy (AION) in polycythemia vera: a case report. Klinische Monatsblätter für Augenheilkunde, 225(5), pp. 504-6. Stuttgart: Ferdinand Enke Verlag 10.1055/s-2008-1027304

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BACKGROUND: Polycythemia vera (PV) is a hemopoetic disorder. Apparently, although thrombosis accounts for the majority of morbidity, AION has not been associated with PV so far. PATIENT AND FINDINGS: A 63 y-old woman with PV was hospitalized because of acute liver failure. She also experienced bilateral painless loss of vision. Bilateral, pale optic disc swelling with flame-like hemorrhages, more pronounced in the right eye, constricted visual fields, and relative afferent papillary defect (RAPD) on the right side were present. Computer tomography scan revealed no signs of intraorbital pathology, elevated intracranial pressure or hemorrhages. CLINICAL COURSE: We interpreted the findings as AION associated with the hyperviscosity syndrome. Liver transplantation had to be carried out in the next days. Three weeks later, vision improved slightly, but RAPD persisted, and disc pallor developed in both eyes. The patient died two months later. DISCUSSION: Central retinal artery and vein occlusions have been described as complications of Essential thrombocythemia, but not of PV. We observed a rare case of bilateral neuropathy suggestive of AION. This condition has so far not been associated with PV.

Item Type:

Journal Article (Further Contribution)

Division/Institute:

04 Faculty of Medicine > Department of Head Organs and Neurology (DKNS) > Clinic of Ophthalmology

UniBE Contributor:

Tönz, Magdalena Sara and Iliev, Milko Emilov

ISSN:

0023-2165

ISBN:

18454412

Publisher:

Ferdinand Enke Verlag

Language:

English

Submitter:

Factscience Import

Date Deposited:

04 Oct 2013 15:05

Last Modified:

04 May 2014 23:20

Publisher DOI:

10.1055/s-2008-1027304

PubMed ID:

18454412

Web of Science ID:

000256237600050

URI:

https://boris.unibe.ch/id/eprint/28225 (FactScience: 118897)

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