Schlapbach, Luregn Jan; Riedel, Thomas; Genitsch, Vera; Nelle, Mathias; McDougall, Felicity Jane (2010). Fatal pulmonary embolism in a premature neonate after twin-to-twin transfusion syndrome. Pediatrics, 126(2), e483-7. Elk Grove Village, Ill.: American Academy of Pediatrics 10.1542/peds.2009-3490
Full text not available from this repository.Thrombotic events are being increasingly recognized during the neonatal period. An infant girl was born at 29 weeks' gestation after a pregnancy complicated by twin-to-twin transfusion syndrome. After an initial uncomplicated clinical course, her oxygen requirement increased, which was interpreted as an early sign of bronchopulmonary dysplasia. At 3 weeks of age, she suddenly collapsed and died of severe pulmonary hypertension. At autopsy, multiple pulmonary artery emboli and several older renal vein thromboses were found. Results of genetic analyses of the infant and her family were negative for thrombophilia. Although embolism represents a frequent emergency in adults, fatal pulmonary embolism has never, to our knowledge, been described for premature infants. This case suggests that thrombotic events are underdiagnosed and that additional studies are needed to define infants at risk and optimal treatment strategies.
Item Type: |
Journal Article (Original Article) |
|---|---|
Division/Institute: |
04 Faculty of Medicine > Department of Gynaecology, Paediatrics and Endocrinology (DFKE) > Clinic of Paediatric Medicine 04 Faculty of Medicine > Service Sector > Institute of Pathology > Immunopathology |
UniBE Contributor: |
Schlapbach, Luregn Jan, Riedel, Thomas, Genitsch Gratwohl, Vera, Nelle, Mathias |
ISSN: |
0031-4005 |
Publisher: |
American Academy of Pediatrics |
Language: |
English |
Submitter: |
Anette van Dorland |
Date Deposited: |
04 Oct 2013 14:13 |
Last Modified: |
05 Dec 2022 14:02 |
Publisher DOI: |
10.1542/peds.2009-3490 |
PubMed ID: |
20603263 |
Web of Science ID: |
000280565700056 |
URI: |
https://boris.unibe.ch/id/eprint/2828 (FactScience: 205748) |
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