M-ficolin in children with cancer

Schlapbach, Luregn J; Thiel, Steffen; Aebi, Christoph; Hirt, Andreas; Leibundgut, Kurt; Jensenius, Jens C; Ammann, Roland A (2011). M-ficolin in children with cancer. Immunobiology, 216(5), pp. 633-8. Amsterdam: Elsevier 10.1016/j.imbio.2010.09.013

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M-ficolin (ficolin-1) is a complement-activating pattern-recognition molecule structurally related to mannan-binding lectin. It is produced by monocytes and neutrophils, and is found in serum. Its biological role is largely unknown. We assessed M-ficolin concentration in serum from pediatric cancer patients. The aim of this study was to explore association of M-ficolin with clinical and hematological parameters, and to investigate whether the risk of chemotherapy-related infections was related to M-ficolin concentrations in serum.

Item Type:

Journal Article (Original Article)

Division/Institute:

04 Faculty of Medicine > Department of Gynaecology, Paediatrics and Endocrinology (DFKE) > Clinic of Paediatric Medicine

UniBE Contributor:

Schlapbach, Luregn Jan; Aebi, Christoph; Hirt, Andreas; Leibundgut, Kurt and Ammann, Roland

ISSN:

0171-2985

Publisher:

Elsevier

Language:

English

Submitter:

Factscience Import

Date Deposited:

04 Oct 2013 14:13

Last Modified:

06 Dec 2013 13:23

Publisher DOI:

10.1016/j.imbio.2010.09.013

PubMed ID:

21112665

Web of Science ID:

000290922500011

URI:

https://boris.unibe.ch/id/eprint/2831 (FactScience: 205752)

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