Targeting vessels to treat hepatocellular carcinoma

Romanque, Pamela; Piguet, Anne-Christine; Dufour, Jean-François (2008). Targeting vessels to treat hepatocellular carcinoma. Clinical science, 114(7), pp. 467-77. London: Portland 10.1042/CS20070310

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The process of blood vessel proliferation, known as angiogenesis, is essential during embryonic development and organogenesis. In adult life, it participates in normal tissue repair, wound healing, and cyclical growth of the corpus luteum and the endometrium. Crucial as it is, angiogenesis can become pathological, and abnormal angiogenesis contributes to the pathogenesis of inflammatory and neoplasic diseases. The present review highlights the evidence for the role of angiogenesis in HCC (hepatocellular carcinoma) and discusses the increasing importance of inhibitors of angiogenesis in HCC therapy.

Item Type:

Journal Article (Further Contribution)

Division/Institute:

04 Faculty of Medicine > Service Sector > Institute of Clinical Pharmacology and Visceral Research (discontinued)
04 Faculty of Medicine > Department of Gastro-intestinal, Liver and Lung Disorders (DMLL) > Clinic of Visceral Surgery and Medicine > Hepatology

UniBE Contributor:

Romanque, Pamela; Piguet, Anne Christine and Dufour, Jean-François

ISSN:

0143-5221

ISBN:

18302534

Publisher:

Portland

Language:

English

Submitter:

Factscience Import

Date Deposited:

04 Oct 2013 15:05

Last Modified:

04 May 2014 23:20

Publisher DOI:

10.1042/CS20070310

PubMed ID:

18302534

Web of Science ID:

000255358700002

URI:

https://boris.unibe.ch/id/eprint/28361 (FactScience: 120278)

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