Information processing in long delay memory-guided saccades: further insights from TMS

Nyffeler, Thomas; Pierrot-Deseilligny, Charles; Pflugshaupt, Tobias; von Wartburg, Roman; Hess, Christian W; Müri, René M (2004). Information processing in long delay memory-guided saccades: further insights from TMS. Experimental brain research, 154(1), pp. 109-12. Berlin: Springer-Verlag; http://www.springer.de 10.1007/s00221-003-1663-6

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The performance of memory-guided saccades with two different delays (3 s and 30 s of memorisation) was studied in eight subjects. Single pulse transcranial magnetic stimulation (TMS) was applied simultaneously over the left and right dorsolateral prefrontal cortex (DLPFC) 1 s after target presentation. In both delays, stimulation significantly increased the percentage of error in amplitude of memory-guided saccades. Furthermore, the interfering effect of TMS was significantly higher in the short delay compared to that of the long delay paradigm. The results are discussed in the context of a mixed model of spatial working memory control including two components: First, serial information processing with a predominant role of the DLPFC during the early period of memorisation and, second, parallel information processing, which is independent from the DLPFC, operating during longer delays.

Item Type:

Journal Article (Original Article)

Division/Institute:

04 Faculty of Medicine > Department of Head Organs and Neurology (DKNS) > Clinic of Neurology

UniBE Contributor:

Nyffeler, Thomas and Hess, Christian Walter

ISSN:

0014-4819

ISBN:

14578999

Publisher:

Springer-Verlag; http://www.springer.de

Language:

English

Submitter:

Factscience Import

Date Deposited:

04 Oct 2013 15:05

Last Modified:

23 Oct 2019 00:07

Publisher DOI:

10.1007/s00221-003-1663-6

PubMed ID:

14578999

Web of Science ID:

000187127600013

BORIS DOI:

10.7892/boris.28434

URI:

https://boris.unibe.ch/id/eprint/28434 (FactScience: 120735)

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