Spinal MRI supporting myelopathic origin of early symptoms in unsuspected cobalamin deficiency

Fritschi, Jürg; Sturzenegger, Matthias (2003). Spinal MRI supporting myelopathic origin of early symptoms in unsuspected cobalamin deficiency. European neurology, 49(3), pp. 146-50. Basel: Karger 10.1159/000069087

Full text not available from this repository. (Request a copy)

We report two patients with subjectively progressive sensory symptoms and gait disturbance due to cobalamin deficiency, but only slight or absent abnormalities on neurological examination. In both patients, spinal MRI provided evidence for a myelopathic origin of the symptoms, disclosing characteristic T(2) hyperintense signal alterations confined to the posterior columns of the cervical and thoracic spinal cord. The patients illustrate the early clinical presentation of subacute combined degeneration (SCD) with a sensory neuropathy starting with acroparesthesia and Lhermitte's sign. Furthermore, the diagnostic value of spinal MRI for early diagnosis of SCD with characteristic findings is highlighted.

Item Type:

Journal Article (Further Contribution)

Division/Institute:

04 Faculty of Medicine > Department of Head Organs and Neurology (DKNS) > Clinic of Neurology

UniBE Contributor:

Strasser, Maja Christine

ISSN:

0014-3022

ISBN:

12646757

Publisher:

Karger

Language:

English

Submitter:

Factscience Import

Date Deposited:

04 Oct 2013 15:05

Last Modified:

04 May 2014 23:20

Publisher DOI:

10.1159/000069087

PubMed ID:

12646757

Web of Science ID:

000182016800004

URI:

https://boris.unibe.ch/id/eprint/28502 (FactScience: 121014)

Actions (login required)

Edit item Edit item
Provide Feedback