The differential effects of thiazolidindiones on atherogenic dyslipidemia in type 2 diabetes: what is the clinical significance?

Rizzo, Manfredi; Christ, Emanuel R; Rini, Giovam Battista; Spinas, Giatgen A; Berneis, Kaspar (2008). The differential effects of thiazolidindiones on atherogenic dyslipidemia in type 2 diabetes: what is the clinical significance? Expert opinion on pharmacotherapy, 9(13), pp. 2295-303. London: Informa Healthcare 10.1517/14656560802321903

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Diabetic dyslipidemia is typically characterized by an increase in plasma triglycerides, a decrease in high-density lipoprotein cholesterol and a concomitant increase in atherogenic small dense low-density lipoproteins. Thiazolidindiones are able to lower the levels of fasting glucose and glycated hemoglobin significantly by improving insulin sensitivity, as well as improving some aspects of diabetic dyslipidemia: total cholesterol, low-density lipoprotein cholesterol and high-density lipoprotein cholesterol tend to increase while triglycerides are generally decreased.

Item Type:

Journal Article (Original Article)

Division/Institute:

04 Faculty of Medicine > Department of Gynaecology, Paediatrics and Endocrinology (DFKE) > Clinic of Endocrinology, Diabetology and Clinical Nutrition

UniBE Contributor:

Christ, Emanuel

ISSN:

1465-6566

ISBN:

18710354

Publisher:

Informa Healthcare

Language:

English

Submitter:

Factscience Import

Date Deposited:

04 Oct 2013 15:06

Last Modified:

05 Dec 2022 14:20

Publisher DOI:

10.1517/14656560802321903

PubMed ID:

18710354

Web of Science ID:

000259105400008

URI:

https://boris.unibe.ch/id/eprint/28560 (FactScience: 121530)

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