A case of maternal herpes simplex virus encephalitis during late pregnancy

Sellner, Johann; Buonomano, Roberto; Nedeltchev, Krassen; Findling, Oliver; Schroth, Gerhard; Surbek, Daniel; Leib, Stephen L. (2009). A case of maternal herpes simplex virus encephalitis during late pregnancy. Nature clinical practice - neurology, 5(1), pp. 51-56. New York, N.Y.: Nature Publishing Group 10.1038/ncpneuro0972

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BACKGROUND: A pregnant 25-year-old woman at 32 weeks' gestation was admitted to an emergency unit after her husband had found her drowsy and with her tongue bitten. The day before admission, the patient had developed a fever of 39 degrees C, was suffering from headaches, was nauseated and had vomited. On admission, she had anterograde and retrograde amnesia, but no somatic neurological deficits were detected. INVESTIGATIONS: Routine laboratory testing, lumbar puncture, cerebrospinal fluid analysis, routine bacteriology, brain MRI, and polymerase chain reaction testing for neurotropic viruses including herpes simplex virus types 1 and 2. DIAGNOSIS: Maternal herpes simplex virus type 1 encephalitis. MANAGEMENT: Antiviral and anticonvulsive therapy, supportive treatment, and cesarean section.

Item Type:

Journal Article (Further Contribution)

Division/Institute:

04 Faculty of Medicine > Service Sector > Institute for Infectious Diseases
04 Faculty of Medicine > Department of Gynaecology, Paediatrics and Endocrinology (DFKE) > Clinic of Gynaecology
04 Faculty of Medicine > Department of Radiology, Neuroradiology and Nuclear Medicine (DRNN) > Institute of Diagnostic and Interventional Neuroradiology
04 Faculty of Medicine > Department of Head Organs and Neurology (DKNS) > Clinic of Neurology
04 Faculty of Medicine > Department of Haematology, Oncology, Infectious Diseases, Laboratory Medicine and Hospital Pharmacy (DOLS) > Clinic of Infectiology
04 Faculty of Medicine > Pre-clinic Human Medicine > BioMedical Research (DBMR) > DCR Unit Sahli Building > Forschungsgruppe Neurologie

UniBE Contributor:

Sellner, Johann; Buonomano, Roberto; Nedeltchev, Krassen; Findling, Oliver; Schroth, Gerhard; Surbek, Daniel and Leib, Stephen

Subjects:

500 Science > 570 Life sciences; biology
600 Technology > 610 Medicine & health

ISSN:

1745-834X

Publisher:

Nature Publishing Group

Language:

English

Submitter:

Factscience Import

Date Deposited:

04 Oct 2013 15:06

Last Modified:

08 Jul 2015 09:42

Publisher DOI:

10.1038/ncpneuro0972

PubMed ID:

19129790

Web of Science ID:

000262294300012

BORIS DOI:

10.7892/boris.28588

URI:

https://boris.unibe.ch/id/eprint/28588 (FactScience: 121907)

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