Multimodal target correction by local bone registration: a PET/CT evaluation

Oliveira-Santos, Thiago; Weitzel, Thilo; Klaeser, Bernd; Krause, Thomas; Nolte, Lutz-Peter; Weber, Stefan; Reyes, Mauricio (2010). Multimodal target correction by local bone registration: a PET/CT evaluation. IEEE Engineering in Medicine and Biology Society conference proceedings, 2010, pp. 5616-5619. Piscataway, N.J.: IEEE Service Center 10.1109/IEMBS.2010.5626797

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PET/CT guidance for percutaneous interventions allows biopsy of suspicious metabolically active bone lesions even when no morphological correlation is delineable in the CT images. Clinical use of PET/CT guidance with conventional step-by-step technique is time consuming and complicated especially in cases in which the target lesion is not shown in the CT image. Our recently developed multimodal instrument guidance system (IGS) for PET/CT improved this situation. Nevertheless, bone biopsies even with IGS have a trade-off between precision and intervention duration which is proportional to patient and personnel exposure to radiation. As image acquisition and reconstruction of PET may take up to 10 minutes, preferably only one time consuming combined PET/CT acquisition should be needed during an intervention. In case of required additional control images in order to check for possible patient movements/deformations, or to verify the final needle position in the target, only fast CT acquisitions should be performed. However, for precise instrument guidance accounting for patient movement and/or deformation without having a control PET image, it is essential to be able to transfer the position of the target as identified in the original PET/CT to a changed situation as shown in the control CT.

Item Type:

Journal Article (Original Article)

Division/Institute:

04 Faculty of Medicine > Pre-clinic Human Medicine > Institute for Surgical Technology & Biomechanics ISTB
04 Faculty of Medicine > Department of Radiology, Neuroradiology and Nuclear Medicine (DRNN) > Clinic of Nuclear Medicine

UniBE Contributor:

Oliveira Dos Santos, Thiago; Weitzel, Thilo; Nolte, Lutz-Peter; Weber, Stefan and Reyes Aguirre, Mauricio Antonio

ISSN:

1557-170X

Publisher:

IEEE Service Center

Language:

English

Submitter:

Mauricio Antonio Reyes Aguirre

Date Deposited:

04 Oct 2013 14:13

Last Modified:

06 Jan 2015 10:04

Publisher DOI:

10.1109/IEMBS.2010.5626797

PubMed ID:

21096492

BORIS DOI:

10.7892/boris.2868

URI:

https://boris.unibe.ch/id/eprint/2868 (FactScience: 205803)

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