Metabolic imaging allows early prediction of response to vandetanib

Walter, Martin A; Benz, Matthias R; Hildebrandt, Isabel J; Laing, Rachel E; Hartung, Verena; Damoiseaux, Robert D; Bockisch, Andreas; Phelps, Michael E; Czernin, Johannes; Weber, Wolfgang A (2011). Metabolic imaging allows early prediction of response to vandetanib. Journal of nuclear medicine, 52(2), pp. 231-40. New York, N.Y.: Society of Nuclear Medicine 10.2967/jnumed.110.081745

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The RET (rearranged-during-transfection protein) protooncogene triggers multiple intracellular signaling cascades regulating cell cycle progression and cellular metabolism. We therefore hypothesized that metabolic imaging could allow noninvasive detection of response to the RET inhibitor vandetanib in vivo.

Item Type:

Journal Article (Further Contribution)

Division/Institute:

04 Faculty of Medicine > Department of Radiology, Neuroradiology and Nuclear Medicine (DRNN) > Clinic of Nuclear Medicine

UniBE Contributor:

Walter, Martin Alexander

ISSN:

0161-5505

Publisher:

Society of Nuclear Medicine

Language:

English

Submitter:

Factscience Import

Date Deposited:

04 Oct 2013 14:13

Last Modified:

17 Mar 2015 19:15

Publisher DOI:

10.2967/jnumed.110.081745

PubMed ID:

21233183

Web of Science ID:

000286594900015

URI:

https://boris.unibe.ch/id/eprint/2882 (FactScience: 205821)

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