The ventro-medial prefrontal cortex: a major link between the autonomic nervous system, regulation of emotion, and stress reactivity?

Hänsel, Alexander; von Känel, Roland (2008). The ventro-medial prefrontal cortex: a major link between the autonomic nervous system, regulation of emotion, and stress reactivity? BioPsychoSocial medicine, 2, p. 21. London: BioMed Central 10.1186/1751-0759-2-21

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ABSTRACT: Recent progress in neuroscience revealed diverse regions of the CNS which moderate autonomic and affective responses. The ventro-medial prefrontal cortex (vmPFC) plays a key role in these regulations. There is evidence that vmPFC activity is associated with cardiovascular changes during a motor task that are mediated by parasympathetic activity. Moreover, vmPFC activity makes important contributions to regulations of affective and stressful situations.This review selectively summarizes literature in which vmPFC activation was studied in healthy subjects as well as in patients with affective disorders. The reviewed literature suggests that vmPFC activity plays a pivotal role in biopsychosocial processes of disease. Activity in the vmPFC might link affective disorders, stressful environmental conditions, and immune function.

Item Type:

Journal Article (Original Article)

Division/Institute:

?? DCD5A442B9C7E17DE0405C82790C4DE2 ??
04 Faculty of Medicine > Department of Head Organs and Neurology (DKNS) > Clinic of Neurology > Centre of Competence for Psychosomatic Medicine

UniBE Contributor:

Hänsel, Alexander and von Känel, Roland

ISSN:

1751-0759

ISBN:

18986513

Publisher:

BioMed Central

Language:

English

Submitter:

Factscience Import

Date Deposited:

04 Oct 2013 15:06

Last Modified:

27 Dec 2019 09:20

Publisher DOI:

10.1186/1751-0759-2-21

PubMed ID:

18986513

BORIS DOI:

10.7892/boris.29000

URI:

https://boris.unibe.ch/id/eprint/29000 (FactScience: 132928)

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