Serduc, Raphaël; Bräuer-Krisch, Elke; Bouchet, Audrey; Renaud, Luc; Brochard, Thierry; Bravin, Alberto; Laissue, Jean Albert; Le Duc, Géraldine (2009). First trial of spatial and temporal fractionations of the delivered dose using synchrotron microbeam radiation therapy. Journal of synchrotron radiation, 16(Pt 4), pp. 587-90. Oxford: Blackwell Publishing 10.1107/S0909049509012485
Full text not available from this repository. (Request a copy)The technical feasibility of temporal and spatial fractionations of the radiation dose has been evaluated using synchrotron microbeam radiation therapy for brain tumors in rats. A significant increase in lifespan (216%, p < 0.0001) resulted when three fractions of microbeam irradiation were applied to the tumor through three different ports, orthogonal to each other, at 24 h intervals. However, there were no long-term survivors, and immunohistological studies revealed that 9 L tumors were not entirely ablated.
Item Type: |
Journal Article (Original Article) |
|---|---|
Division/Institute: |
04 Faculty of Medicine > Service Sector > Institute of Pathology |
UniBE Contributor: |
Laissue, Jean |
ISSN: |
0909-0495 |
ISBN: |
19535875 |
Publisher: |
Blackwell Publishing |
Language: |
English |
Submitter: |
Factscience Import |
Date Deposited: |
04 Oct 2013 15:08 |
Last Modified: |
05 Dec 2022 14:21 |
Publisher DOI: |
10.1107/S0909049509012485 |
PubMed ID: |
19535875 |
Web of Science ID: |
000267047100020 |
URI: |
https://boris.unibe.ch/id/eprint/30014 (FactScience: 165770) |
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