Interictal arterial spin-labeling MRI perfusion in intractable epilepsy

Pendse, N; Wissmeyer, M; Altrichter, S; Vargas, M; Delavelle, J; Viallon, M; Federspiel, A; Seeck, M; Schaller, K; Lövblad, K O (2010). Interictal arterial spin-labeling MRI perfusion in intractable epilepsy. Journal of neuroradiology, 37(1), pp. 60-63. Issy-les-Moulineaux (F): Elsevier Masson 10.1016/j.neurad.2009.05.006

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Magnetic resonance imaging (MRI) is required for the investigation of surgically intractable epilepsy. In addition to the standard MRI techniques, perfusion sequences can be added to improve visualization of underlying pathological changes. Arterial spin-labeling (ASL) MRI perfusion does not require contrast administration and, for this reason, may have advantages in these patients.

We report here on 16 patients with epilepsy who underwent MRI of the brain with ASL and positron emission tomography (PET).

Despite a slightly reduced resolution with ASL, we found a correlation between ASL, PET and electrophysiological data, with hypoperfusion on ASL that corresponded with hypoperfusion on interictal PET.

Given the correlation between ASL and PET and electrophysiology, perfusion with ASL could become part of the standard work-up in patients with epilepsy.

Item Type:

Journal Article (Original Article)


04 Faculty of Medicine > University Psychiatric Services > University Hospital of Psychiatry and Psychotherapy > Psychiatric Neurophysiology [discontinued]

UniBE Contributor:

Federspiel, Andrea




Elsevier Masson


Factscience Import

Date Deposited:

04 Oct 2013 14:13

Last Modified:

15 Feb 2014 11:27

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Additional Information:

This article belongs to a special issue XIIe Journées de neuroradiologie de langue française - XXXVIIe congrès annuel de la Société française de neuroradiologie. Congrès SFNR 2010

URI: (FactScience: 206204)

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