Yawalkar, N (2009). Drug hypersensitivity. Acta clinica belgica, 64(6), pp. 529-33. Brussels: Acta clinica belgica
Full text not available from this repository.Drug hypersensitivity represents an immune-mediated reaction to a drug. Although several drug hypersensitivity reactions are confined to the skin and rather mild, some may be life threatening and also involve further organs such as liver, kidney and bone marrow. The exact pathogenesis of many drug hypersensitivity reactions is still obscure. In this review the concepts on how small molecular drugs can activate the immune system are discussed and the hapten, prohapten and p-i concept are explained. Furthermore, the classification of drug hypersensitivity reactions and some common and severe clinical manifestations of drug-induced T cell mediated reactions are presented.
Item Type: |
Journal Article (Original Article) |
|---|---|
Division/Institute: |
04 Faculty of Medicine > Department of Dermatology, Urology, Rheumatology, Nephrology, Osteoporosis (DURN) > Clinic of Dermatology |
UniBE Contributor: |
Yawalkar, Nikhil |
ISSN: |
0001-5512 |
ISBN: |
20101877 |
Publisher: |
Acta clinica belgica |
Language: |
English |
Submitter: |
Factscience Import |
Date Deposited: |
04 Oct 2013 15:09 |
Last Modified: |
05 Dec 2022 14:21 |
PubMed ID: |
20101877 |
Web of Science ID: |
000273102800010 |
URI: |
https://boris.unibe.ch/id/eprint/30393 (FactScience: 193756) |
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