Drug hypersensitivity

Yawalkar, N (2009). Drug hypersensitivity. Acta clinica belgica, 64(6), pp. 529-33. Brussels: Acta clinica belgica

Full text not available from this repository. (Request a copy)

Drug hypersensitivity represents an immune-mediated reaction to a drug. Although several drug hypersensitivity reactions are confined to the skin and rather mild, some may be life threatening and also involve further organs such as liver, kidney and bone marrow. The exact pathogenesis of many drug hypersensitivity reactions is still obscure. In this review the concepts on how small molecular drugs can activate the immune system are discussed and the hapten, prohapten and p-i concept are explained. Furthermore, the classification of drug hypersensitivity reactions and some common and severe clinical manifestations of drug-induced T cell mediated reactions are presented.

Item Type:

Journal Article (Original Article)

Division/Institute:

04 Faculty of Medicine > Department of Dermatology, Urology, Rheumatology, Nephrology, Osteoporosis (DURN) > Clinic of Dermatology

UniBE Contributor:

Yawalkar, Nikhil

ISSN:

0001-5512

ISBN:

20101877

Publisher:

Acta clinica belgica

Language:

English

Submitter:

Factscience Import

Date Deposited:

04 Oct 2013 15:09

Last Modified:

04 May 2014 23:22

PubMed ID:

20101877

Web of Science ID:

000273102800010

URI:

https://boris.unibe.ch/id/eprint/30393 (FactScience: 193756)

Actions (login required)

Edit item Edit item
Provide Feedback