Coronary artery disease is common in asymptomatic patients with signs of myocardial ischemia

Schoenenberger, Andreas W; Jamshidi, Peiman; Zuber, Michel; Stuck, Andreas E; Pfisterer, Matthias; Erne, Paul (2009). Coronary artery disease is common in asymptomatic patients with signs of myocardial ischemia. European journal of internal medicine, 20(6), pp. 607-10. Roma: Pozzi 10.1016/j.ejim.2009.04.001

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BACKGROUND: The incidence of coronary artery disease (CAD) in totally asymptomatic patients with myocardial ischemia during stress testing is unknown. METHODS: 54 patients with asymptomatic myocardial ischemia participated in the Swiss Interventional Study on Silent Ischemia type I (SWISSI I). Asymptomatic myocardial ischemia was verified by bicycle ergometry and stress imaging (echocardiography or scintigraphy). Findings from coronary angiographies in the course of the study constituted the main outcome. RESULTS: Of the 54 study participants, 29 patients (53.7%) underwent coronary angiography. CAD was found in 27 of 29 patients (93.1%). In those 27 patients with CAD, 9 patients (33.3%) suffered from single vessel disease, 9 patients (33.3%) from two vessel disease, and 9 patients (33.3%) from triple vessel disease. Two patients showed left main coronary artery stenosis. CONCLUSION: This study shows a high incidence of relevant CAD among totally asymptomatic patients with myocardial ischemia during stress testing. Previously healthy subjects with exercise-induced ST-segment depression at check-up examinations, even if asymptomatic, should have further diagnostic evaluation.

Item Type:

Journal Article (Original Article)

Division/Institute:

04 Faculty of Medicine > Pre-clinic Human Medicine > Institute of Social and Preventive Medicine
04 Faculty of Medicine > Department of General Internal Medicine (DAIM) > Geriatric Clinic

UniBE Contributor:

Schoenenberger, Andreas and Stuck, Andreas

ISSN:

0953-6205

Publisher:

Pozzi

Language:

English

Submitter:

Factscience Import

Date Deposited:

04 Oct 2013 15:10

Last Modified:

30 Jun 2015 16:51

Publisher DOI:

10.1016/j.ejim.2009.04.001

PubMed ID:

19782922

Web of Science ID:

000271359100011

BORIS DOI:

10.7892/boris.30631

URI:

https://boris.unibe.ch/id/eprint/30631 (FactScience: 194882)

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