Bulky extramedullary hematopoiesis is not a rare complication of congenital dyserythropoietic anemia

Heimpel, Hermann; Dührsen, Ulrich; Hofbauer, P; Rigamonti-Wermlinger, V; Kreuser, Ernst-Dietrich; Schwarz, Klaus; Solenthaler, Max; Pauls, S (2009). Bulky extramedullary hematopoiesis is not a rare complication of congenital dyserythropoietic anemia. Annals of hematology, 88(10), pp. 937-41. Berlin: Springer 10.1007/s00277-009-0735-5

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Bulky extramedullary hematopoiesis, usually detected in the thorax by imaging techniques, is a well-known complication in many types of congenital anemias. Here, we describe 12 cases of congenital dyserythropoietic anemia with extramedullary hematopoiesis which was always located in the paravertebral space of the thoracic spine and in other paraspinal regions in a few cases. All bulks were originally detected in chest radiographs and confirmed by imaging techniques such as computed tomography and/or magnetic resonance imaging. In some cases, thoracotomy was performed for suspected malignancy. Although the true prevalence is not known, paravertebral masses in patients with CDA of any type are not uncommon and should be the first differential diagnosis considered when masses adjacent to the spine are detected in this disorder.

Item Type:

Journal Article (Further Contribution)


04 Faculty of Medicine > Department of Haematology, Oncology, Infectious Diseases, Laboratory Medicine and Hospital Pharmacy (DOLS) > Clinic of Haematology and Central Haematological Laboratory

UniBE Contributor:

Solenthaler, Max








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Date Deposited:

04 Oct 2013 15:10

Last Modified:

04 May 2014 23:22

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https://boris.unibe.ch/id/eprint/30916 (FactScience: 195278)

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