The role of admission blood glucose in outcome prediction of surviving patients with multiple injuries

Kreutziger, Janett; Schlaepfer, Jessica; Wenzel, Volker; Constantinescu, Mihai Adrian (2009). The role of admission blood glucose in outcome prediction of surviving patients with multiple injuries. Journal of trauma - injury, infection, and critical care, 67(4), pp. 704-8. Baltimore, Md.: Lippincott, Williams, & Wilkins 10.1097/TA.0b013e3181b22e37

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BACKGROUND: Recent literature demonstrates hyperglycemia to be common in patients with trauma and associated with poor outcome in patients with traumatic brain injury and critically ill patients. The goal of this study was to analyze the impact of admission blood glucose on the outcome of surviving patients with multiple injuries. METHODS: Patients' charts (age >16) admitted to the emergency room of the University Hospital of Berne, Switzerland, between January 1, 2002, and December 31, 2004, with an Injury Severity Score >or=17 and more than one severely injured organ system were reviewed retrospectively. Outcome measurements included morbidity, intensive care unit, and hospital length of stay. RESULTS: The inclusion criteria were met by 555 patients, of which 108 (19.5%) patients died. After multiple regression analysis, admission blood glucose proved to be an independent predictor of posttraumatic morbidity (p < 0.0001), intensive care unit, and hospital length of stay (p < 0.0001), despite intensified insulin therapy on the intensive care unit. CONCLUSIONS: In this population of patients with multiple injuries, hyperglycemia on admission was strongly associated with increased morbidity, especially infections, prolonged intensive care unit, and hospital length of stay independent of injury severity, gender, age, and various biochemical parameters.

Item Type:

Journal Article (Original Article)

Division/Institute:

04 Faculty of Medicine > Department of Orthopaedic, Plastic and Hand Surgery (DOPH) > Clinic of Plastic and Hand Surgery

UniBE Contributor:

Constantinescu, Mihai Adrian

ISSN:

0022-5282

Publisher:

Lippincott, Williams, & Wilkins

Language:

English

Submitter:

Factscience Import

Date Deposited:

04 Oct 2013 15:11

Last Modified:

05 Dec 2022 14:22

Publisher DOI:

10.1097/TA.0b013e3181b22e37

PubMed ID:

19820574

Web of Science ID:

000270747000005

URI:

https://boris.unibe.ch/id/eprint/31449 (FactScience: 196014)

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