In situ fluoride retention and remineralization of incipient carious lesions after the application of different concentrations of fluoride

Altenburger, Markus J; Schirrmeister, Jörg F; Lussi, Adrian; Klasser, Manfred; Hellwig, Elmar (2009). In situ fluoride retention and remineralization of incipient carious lesions after the application of different concentrations of fluoride. European journal of oral sciences, 117(1), pp. 58-63. Chichester: Wiley-Blackwell 10.1111/j.1600-0722.2008.00585.x

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Limited information is available on the time-dependent or dosage-dependent cariostatic efficacy of highly concentrated fluoride compounds. This good clinical practice-conforming, double-blind, placebo-controlled, crossover in situ study tested the hypothesis that a 1.0% amine fluoride fluid is superior to a 0.5% amine fluoride fluid regarding fluoride retention and mineral change in initial caries enamel lesions over a period of 28 d. Fluoride retention was significantly higher after application of the two fluoride fluids compared with placebo but had decreased in both groups to similar levels after only 1 wk. Mineral gain was significantly higher for both verum groups compared with placebo. The use of 1% fluoride fluid resulted in significantly higher remineralization compared with the use of 0.5% fluoride fluid. For both fluoride fluids mineral gain followed a linear relationship with time during the experimental period, indicating a possible further uptake of mineral, even after 4 wk.

Item Type:

Journal Article (Original Article)

Division/Institute:

04 Faculty of Medicine > School of Dental Medicine > Department of Preventive, Restorative and Pediatric Dentistry

UniBE Contributor:

Lussi, Adrian

ISSN:

0909-8836

Publisher:

Wiley-Blackwell

Language:

English

Submitter:

Eveline Carmen Schuler

Date Deposited:

04 Oct 2013 15:12

Last Modified:

25 Jan 2017 12:16

Publisher DOI:

10.1111/j.1600-0722.2008.00585.x

PubMed ID:

19196319

Web of Science ID:

000262510200009

URI:

https://boris.unibe.ch/id/eprint/31647 (FactScience: 196292)

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