Rieben, Robert; Seebach, Jörg D (2005). Xenograft rejection: IgG1, complement and NK cells team up to activate and destroy the endothelium. Trends in immunology, 26(1), pp. 2-5. Oxford: Elsevier Current Trends 10.1016/j.it.2004.11.011
Full text not available from this repository.Acute vascular rejection represents a formidable barrier to clinical xenotransplantation and it is known that this type of rejection can also be initiated by xenoreactive antibodies that have limited complement-activating ability. Using a sophisticated mouse model, a recent study has provided in vivo evidence for the existence of an IgG(1)-mediated vascular rejection, which uniquely depends on both the activation of complement and interactions with FcgammaRIII on natural killer (NK) cells.
Item Type: |
Journal Article (Further Contribution) |
|---|---|
Division/Institute: |
04 Faculty of Medicine > Pre-clinic Human Medicine > BioMedical Research (DBMR) > Forschungsbereich Mu50 > Forschungsgruppe Herz und Gefässe |
UniBE Contributor: |
Rieben, Robert |
ISSN: |
1471-4906 |
Publisher: |
Elsevier Current Trends |
Language: |
English |
Submitter: |
Factscience Import |
Date Deposited: |
04 Oct 2013 15:12 |
Last Modified: |
05 Dec 2022 14:22 |
Publisher DOI: |
10.1016/j.it.2004.11.011 |
PubMed ID: |
15629401 |
Web of Science ID: |
000226566000001 |
URI: |
https://boris.unibe.ch/id/eprint/31677 (FactScience: 196326) |
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