Cardiovascular proteomics: implications for clinical applications

Schoenhoff, Florian S; Fu, Qin; Van Eyk, Jennifer E (2009). Cardiovascular proteomics: implications for clinical applications. Clinics in laboratory medicine, 29(1), pp. 87-99. Philadelphia, Pa.: Elsevier 10.1016/j.cll.2009.01.005

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Proteomics is fulfilling its potential and beginning to impact the diagnosis and therapy of cardiovascular disease. As de novo proteomics analysis gets more streamlined, and robust high-throughput methods are developed, more and more attention is being directed toward the field of cardiovascular serum and plasma biomarker discovery. To take cardiovascular proteomics from bench to bedside, great care must be taken to achieve reproducible results. Despite technical advances, however, the absolute number of clinical biomarkers thus far discovered by a proteomics approach is small. Although several factors contribute to this lack, one step is to build "translation teams" involving a close collaboration between researchers and clinicians.

Item Type:	Journal Article (Further Contribution)
Division/Institute:	04 Faculty of Medicine > Department of Cardiovascular Disorders (DHGE) > Clinic of Heart Surgery
UniBE Contributor:	Schönhoff, Florian
ISSN:	0272-2712
Publisher:	Elsevier
Language:	English
Submitter:	Factscience Import
Date Deposited:	04 Oct 2013 15:12
Last Modified:	27 Feb 2024 14:29
Publisher DOI:	10.1016/j.cll.2009.01.005
PubMed ID:	19389553
Web of Science ID:	000266380300008
URI:	https://boris.unibe.ch/id/eprint/31717 (FactScience: 196377)