Vanscheidt, Wolfgang; Hunziker, Thomas (2009). Repigmentation by outer-root-sheath-derived melanocytes: proof of concept in vitiligo and leucoderma. Dermatology, 218(4), pp. 342-3. Basel: Karger 10.1159/000197467
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BACKGROUND: Treatment of depigmented skin is an unmet medical need. OBJECTIVE: Melanocytes or stem cells thereof residing in the outer root sheath (ORS) of hair follicles might be used to repigment skin. METHODS: After de-epidermisation, autologous ORS cell solutions were applied to 5 patients with vitiligo and 1 with leucoderma. RESULTS: Stable repigmentation in a variable percentage was documented in all the patients. CONCLUSION: Applying ORS-derived melanocytes is a promising technology to improve autologous melanocyte transplantation.
Item Type: |
Journal Article (Original Article) |
|---|---|
Division/Institute: |
04 Faculty of Medicine > Department of Dermatology, Urology, Rheumatology, Nephrology, Osteoporosis (DURN) > Clinic of Dermatology |
UniBE Contributor: |
Hunziker, Thomas |
ISSN: |
1018-8665 |
Publisher: |
Karger |
Language: |
English |
Submitter: |
Factscience Import |
Date Deposited: |
04 Oct 2013 15:13 |
Last Modified: |
21 Jun 2023 12:00 |
Publisher DOI: |
10.1159/000197467 |
PubMed ID: |
19174603 |
Web of Science ID: |
000265799000009 |
BORIS DOI: |
10.48350/32042 |
URI: |
https://boris.unibe.ch/id/eprint/32042 (FactScience: 196885) |
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