Long-term quality of life after hepatic resection: health is not simply the absence of disease

Banz, Vanessa M; Inderbitzin, Daniel; Fankhauser, Regula; Studer, Peter; Candinas, Daniel (2009). Long-term quality of life after hepatic resection: health is not simply the absence of disease. World journal of surgery, 33(7), pp. 1473-80. New York, N.Y.: Springer-Verlag 10.1007/s00268-009-0032-4

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BACKGROUND: Due to advances in operative methods and perioperative care, mortality and morbidity following major hepatic resection have decreased substantially, making long-term quality of life (QoL) an increasingly prominent issue. We evaluated whether postoperative diagnosis was associated with long-term QoL and health in patients requiring hepatic surgery for benign or malignant disease. METHODS: QoL was evaluated using the European Organization for Research and Treatment of Cancer Quality of Life Questionnaire Core-30 and the liver-specific QLQ-LMC21 module. RESULTS: Between 2002 and 2006, 249 patients underwent hepatic surgery for malignant (76%) and benign (24%) conditions. One hundred thirty-five patients were available for QoL analysis after a mean of 26.5 months. There was no statistical difference in global QoL scores between patients with malignant and benign diseases (p = 0.367). Neither the extent of the resection (> or =2 segments vs. <2 segments; p = 0.975; OR = 0.988; 95% CI = 0.461-2.119) nor patient age had a significant influence on overall QoL (p = 0.092). CONCLUSIONS: These results indicate that long-term QoL for patients who underwent liver resection for malignant disease is quite good and that a poor clinical prognosis does not seem to correlate with a poor QoL.

Item Type:

Journal Article (Original Article)

Division/Institute:

04 Faculty of Medicine > Department of Gastro-intestinal, Liver and Lung Disorders (DMLL) > Clinic of Visceral Surgery and Medicine > Visceral Surgery

UniBE Contributor:

Inderbitzin, Daniel and Candinas, Daniel

ISSN:

0364-2313

Publisher:

Springer-Verlag

Language:

English

Submitter:

Factscience Import

Date Deposited:

04 Oct 2013 15:13

Last Modified:

24 Oct 2019 20:48

Publisher DOI:

10.1007/s00268-009-0032-4

PubMed ID:

19384460

Web of Science ID:

000266789700022

BORIS DOI:

10.7892/boris.32299

URI:

https://boris.unibe.ch/id/eprint/32299 (FactScience: 197358)

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