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5.1215 0 TD
0 Tc
[ (March) -332.5 (27\054) -340.9 (2) -0.1 (009) ] TJ
/F3 1 Tf
-29.2903 -1.7885 TD
0.0001 Tc
(Copyright\072) Tj
/F7 1 Tf
5.4955 0 TD
0 Tc
<01> Tj
/F4 1 Tf
1.2113 0 TD
[ (2009) -390.5 (Bryan\054) -397 (Jr\056) -395.6 (et) -386.4 (al\056) -392.8 (This) -396.9 (is) -392.2 (an) -391.6 (open\055access) -402.8 (article) -395.5 (distributed) -402.1 (under) -389.6 (t) 0 (he) -395.3 (terms) -397.1 (o) -0.1 (f) -392.6 (t) 0 (he) -387.1 (Cre) -9.4 (ative) -394.3 (Commons) -390.3 (Attrib) -11.3 (ution) -391.4 (License\054) -399.6 (which) -399.3 (permits) ] TJ
-6.7068 -1.1462 TD
[ (unrestricted) -342.4 (use\054) -336.6 (distri) -10.9 (bution\054) -334.8 (and) -333.6 (reprod) -15.1 (u) -0.1 (ction) -334.5 (i) 0 (n) -332.7 (a) 0 (ny) -338.2 (medium) -10.8 (\054) -328.5 (p) -0.1 (rovide) -11.1 (d) -332.2 (the) -338.3 (original) -341.4 (author) -339.6 (and) -333.6 (s) 0 (ource) -337.2 (are) -341.1 (credited\056) ] TJ
/F3 1 Tf
0 -1.7803 TD
0.0001 Tc
(Funding\072) Tj
/F4 1 Tf
4.7069 0 TD
0 Tc
[ (This) -421.3 (work) -422.7 (w) -0.1 (as) -427.4 (supported) -427.9 (by) -423.2 (NSF) -422.6 (Award) ] TJ
/F8 1 Tf
18.0961 0 TD
(\043) Tj
/F4 1 Tf
0.8211 0 TD
(\050ASE) Tj
/F9 1 Tf
1.8779 0 TD
(\053) Tj
/F4 1 Tf
0.5528 0 TD
[ (NHS\051\050dms\051) -12.4 (0) -0.1 (428715) -429.4 (a) 0 (nd) -423 (NIH) -416.2 (g) -0.1 (r) -10.2 (ants) ] TJ
/F8 1 Tf
15.5028 0 TD
(\043) Tj
/F4 1 Tf
0.8211 0 TD
0.0001 Tc
[ (U54\055L) -11.7 (M008748\054) ] TJ
/F8 1 Tf
6.9425 0 TD
0 Tc
(\043) Tj
/F4 1 Tf
0.8292 0 TD
0.0001 Tc
[ (R01\055GM25874\054) -426.7 (and) ] TJ
/F8 1 Tf
8.5115 0 TD
0 Tc
(\043) Tj
/F4 1 Tf
0.8292 0 TD
0.0001 Tc
[ (R01\055GM080330\056) -428.8 (N) 0 (o) ] TJ
-59.4911 -1.1462 TD
0 Tc
[ (financial) -455.4 (source) -459.2 (had) -447.4 (a) 0 (ny) -452 (role) -453.6 (in) -454.6 (experiment) -460.3 (design\054) -454.9 (conduct\054) -452 (data) -455.6 (collec) -10.2 (tion\054) -450.8 (analysis\054) -459.7 (or) -451 (interpretat) -12 (ion\054) -450.6 (o) -0.1 (r) -451 (i) 0 (n) -446.5 (t) 0 (he) -452.2 (prepar) -13 (ation\054) -451.4 (review\054) -453.3 (or) -451 (app) -10.9 (rov) ] TJ
63.7464 0 TD
[ (al) -450.8 (of) -449.5 (this) ] TJ
-63.7464 -1.1462 TD
(manuscript\056) Tj
/F3 1 Tf
0 -1.7803 TD
0.0001 Tc
[ (Competing) -341.9 (I) 0.1 (nterest) -11.6 (s) 0.1 (\072) ] TJ
/F4 1 Tf
10.4626 0 TD
0 Tc
[ (The) -333.9 (authors) -342.9 (h) -0.1 (ave) -331.1 (decl) -9.7 (ared) -331.8 (that) -343.3 (no) -334.9 (competing) -337.9 (i) 0 (ntere) -10.8 (sts) -332.1 (exist\056) ] TJ
-10.4626 -1.7885 TD
[ (\052) -331.9 (E\055mail\072) -336.2 (lindqui) -11.3 (st\137admin\100) -11.4 (wi\056mit\056edu) -337.9 (\050SLL\051\073) -341.2 (bab\100mit\056ed) -12.8 (u) -334.1 (\050) 0 (BB\051) ] TJ
/F3 1 Tf
9.9626 0 0 9.9626 58.0535 248.5984 Tm
[ (In) -6.2 (troduction) ] TJ
/F10 1 Tf
8.9663 0 0 8.9663 67.011 230.7401 Tm
[ (\221\221Amyloid\222\222) -239.1 (is) -239 (a) -240.2 (term) -243.1 (used) -238.6 (to) -239.6 (describe) -240.1 (a) -240.2 (particular) -243 (type) -235.1 (of) -241.6 (protein) ] TJ
-0.999 -1.1887 TD
[ (structure) -379.4 (that) -379 (can) -369.7 (be) -377.1 (adopted) -373.2 (by) -375.1 (a) -379.3 (very) -369.5 (wide) -379.5 (variety) -372.1 (of) -374.4 (proteins) ] TJ
T*
[ (with) -312.2 (completely) -316.1 (unrelated) -315.4 (primary) -314.7 (amino) -313.2 (acid) -314 (sequences) -318.1 (\1331\0542\135\056) -311.5 (It) ] TJ
T*
[ (is) -510.9 (a) -505.7 (form) -510.9 (of) -507.2 (protein) -508.6 (aggregation\054) -512.4 (but) -508.9 (of) -507.2 (a) -505.7 (distinct) -508.6 (and) -510.6 (highly) ] TJ
T*
[ (ordered) -424 (type\056) -421.3 (It) -417.2 (has) -419.4 (recently) -419.9 (been) -420.7 (realized) -417.7 (that\054) -426.2 (given) -416.7 (the) -416.5 (right) ] TJ
T*
[ (conditions\054) -694.1 (a) -695.4 (great) -690.8 (many\054) -696.6 (perhaps) -690.2 (most\054) -694.5 (proteins) -694.1 (have) -692 (the) ] TJ
T*
[ (potential) -443.6 (to) -442 (form) -447.7 (amyloids\056) -441.5 (This) -439.9 (appears) -443.3 (to) -442 (be) -446.7 (due) -438.8 (to) -442 (intrinsic) ] TJ
T*
[ (properties) -321.4 (of) -317.5 (the) -315.4 (peptide) -319.1 (backbone\054) -314.9 (a) -316 (finding) -322.4 (of) -311.2 (great) -317.7 (importance) ] TJ
T*
[ (for) -351.9 (understanding) -356.3 (the) -353.3 (evolution) -352.1 (of) -349.1 (protein) -350.5 (folds\056) -353.9 (A) -347.3 (much) -356.6 (smaller) ] TJ
T*
[ (fraction) -294.3 (of) -285.9 (proteins\054) -286 (and) -289.3 (protein) -293.6 (fragments\054) -287.7 (assemble) -287.8 (into) -293.2 (amyloid) ] TJ
T*
[ (under) -530.1 (normal) -522.9 (physiological) -526.4 (conditions\054) -529.7 (and) -523.3 (these) -525.4 (are) -526.7 (of) -526.2 (great) ] TJ
T*
[ (interest) -341.1 (in) -331.8 (diverse) -337.1 (aspects) -333.4 (of) -336.5 (biology) -333.8 (and) -333.6 (medicine\1333\135\056) ] TJ
0.999 -1.2077 TD
[ (Many) -391.7 (amyloids) -394.3 (first) -395.1 (came) -388.8 (to) -391.4 (our) -392.7 (attention) -393.3 (because) -392.4 (they) -394.8 (were) ] TJ
-0.999 -1.1887 TD
[ (associated) -803.5 (with) -799.1 (a) -802.9 (wide) -803.2 (variety) -802.1 (of) -798.1 (diseases\054) -805.7 (from) -795.4 (systemic) ] TJ
T*
[ (amyloidoses) -281.4 (to) -277.6 (neurodegenerative) -282.6 (diseases) -278 (such) -281.8 (as) -273.9 (Alzheimer\222s\1334\135\056) ] TJ
0 -1.195 TD
[ (It) -341.4 (had) -333.6 (initially) -343.4 (been) -332.2 (assumed\054) -339.2 (therefore\054) -342.5 (that) -334.8 (amyloids) -343.7 (were) -335.9 (toxic) ] TJ
0 -1.1887 TD
[ (species\056) -395.6 (This) -395.6 (indeed) -396.8 (may) -396.4 (be) -396.1 (the) -391.2 (case) -396.2 (in) -395.1 (peripheral) -397 (amyloidoses\054) ] TJ
28.6681 21.2007 TD
[ (where) -323.3 (the) -328 (massive) -326.9 (accumulation) -323.3 (of) -323.8 (amyloid) -329 (fibers) -323.5 (may) -326.9 (physically) ] TJ
0 -1.1761 TD
[ (disrupt) -300.1 (normal) -295.3 (tissue) -295.5 (function\1335\135\056) -295.8 (Increasingly\054) -302.2 (however\054) -291.3 (evidence) ] TJ
0 -1.1824 TD
[ (suggests) -281.8 (that) -284.2 (the) -283.8 (formation) -279.2 (of) -279.6 (amyloids) -280.5 (may) -282.6 (more) -280.7 (commonly) -280.7 (be) -282.3 (a) ] TJ
T*
[ (protective) -741.7 (mechanism) -736.4 (which\054) -735.6 (especially) -738 (in) -736.5 (the) -739 (case) -737.6 (of) -734.8 (the) ] TJ
0 -1.1761 TD
[ (neurodegenerative) -586.1 (amyloidoses\054) -575.1 (acts) -573.8 (as) -577.4 (to) -574.7 (sequester) -583.2 (misfolded) ] TJ
0 -1.1824 TD
[ (polypeptides) -336.6 (that) -328.5 (would) -326 (otherwise) -334 (dwell) -328.6 (in) -331.8 (more) -324.9 (toxic\054) -332.1 (and) -327.3 (more) ] TJ
T*
[ (highly) -488.4 (interactive\054) -484 (oligomeric) -486 (species\056) -484.2 (It) -486.8 (has) -482.6 (also) -483.3 (recently) -489.5 (been) ] TJ
0 -1.1761 TD
[ (realized) -449.3 (that) -442.3 (amyloids) -444.9 (serve) -449.5 (important) -440.5 (biological) -451.1 (functions) -444.1 (in) -445.6 (a) ] TJ
0 -1.1824 TD
[ (number) -619.6 (of) -614.7 (different) -625.9 (situations\056) -617.5 (For) -619.9 (example\054) -616.8 (in) -616.4 (melanocytes\054) ] TJ
T*
[ (amyloid) -310 (fibers) -310.8 (formed) -312.6 (by) -311.9 (Pmel17) -311 (play) -313 (a) -309.7 (role) -306.2 (in) -312.9 (the) -309 (production) -312.7 (of) ] TJ
0 -1.1761 TD
[ (melanin\1336\135\054) -604.4 (and) -599.1 (in) -597.4 (bacteria) -606.6 (extracellular) -604.6 (amyloids) -603 (are) -602.5 (a) -600.6 (key) ] TJ
0 -1.1824 TD
[ (feature) -349.1 (of) -349.1 (the) -347 (biofilms) -351.4 (that) -347.4 (are) -349.6 (so) -349.4 (difficult) -352 (to) -347.1 (eradicate) -346.6 (in) -350.8 (various) ] TJ
T*
[ (infectious) -370.3 (processes\1337\135\056) -374.4 (In) -366.9 (fungi\054) -366.5 (a) -373 (special) -367.2 (class) -368.7 (of) -368.1 (self\055templating) ] TJ
0 -1.1761 TD
[ (amyloids) -324.8 (serve) -323.1 (as) -324.5 (elements) -324.5 (of) -323.8 (inheritance\072) -322.7 (these) -323 (bi\055stable) -328.8 (proteins) ] TJ
0 -1.1824 TD
[ (can) -584.7 (persist) -589.1 (as) -583.7 (soluble) -588.3 (or) -583.9 (amyloid) -588.2 (species) -588.7 (and) -586.5 (the) -587.2 (change) -583.9 (in) ] TJ
T*
[ (function) -315.6 (that) -315.8 (occurs) -312.1 (when) -308.8 (with) -312.2 (the) -315.4 (switch) -310.9 (to) -315.5 (the) -315.4 (amyloid) -310 (form\054) -311.5 (is) ] TJ
0 -1.1761 TD
[ (passed) -246.9 (from) -239 (generation) -243.7 (to) -239.6 (generation) -243.7 (as) -242.3 (mother) -242.7 (cells) -240.8 (faithfully) -244.9 (pass) ] TJ
0 -1.1824 TD
[ (amyloid) -278.4 (\050prion\051) -271.8 (templates) -279.1 (through) -272.5 (the) -277.4 (cytoplasm) -274.1 (to) -271.2 (their) -276.7 (daughter) ] TJ
T*
[ (cells\1338\0549\135\056) -400.5 (Such) -402.6 (self\055perpetuating) -406 (prion\055like) -406.8 (switches) -400.8 (in) -395.1 (state) -405.6 (also) ] TJ
ET
0 0 0 1 k
58.054 748.516 496.176 0.51025 re
f
0.957 0.345 0.125 0.027 k
1 i
80.484 760.735 m
80.484 760.299 l
81.761 760.299 l
81.761 760.735 l
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85.588 757.583 l
86.864 757.583 l
86.864 760.735 l
86.864 762.494 85.433 763.925 83.674 763.925 c
81.916 763.925 80.484 762.494 80.484 760.735 c
f
84.733 755.745 m
84.733 755.161 84.261 754.689 83.679 754.689 c
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82.626 756.327 83.097 756.798 83.679 756.798 c
84.261 756.798 84.733 756.327 84.733 755.745 c
f
81.183 755.755 m
81.183 757.125 82.298 758.24 83.668 758.24 c
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86.151 754.385 85.037 753.271 83.668 753.271 c
82.298 753.271 81.183 754.385 81.183 755.755 c
h
79.906 755.755 m
79.906 753.68 81.592 751.994 83.668 751.994 c
85.741 751.994 87.429 753.68 87.429 755.755 c
87.429 757.829 85.741 759.517 83.668 759.517 c
81.592 759.517 79.906 757.829 79.906 755.755 c
f
60.654 754.704 m
61.477 754.704 61.95 755.48 61.95 756.536 c
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60.654 754.704 l
h
60.59 753.736 m
58.998 753.736 58.054 754.945 58.054 756.48 c
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62.334 759.304 63.238 758.063 63.238 756.577 c
63.238 754.8 62.174 753.736 60.597 753.736 c
60.59 753.736 l
f
65.246 756.697 m
65.349 756.672 65.47 756.663 65.654 756.663 c
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65.246 756.697 l
h
64.037 759.143 m
64.414 759.207 64.942 759.256 65.686 759.256 c
66.436 759.256 66.973 759.113 67.333 758.816 c
67.685 758.552 67.909 758.103 67.909 757.577 c
67.909 757.039 67.741 756.592 67.414 756.296 c
66.998 755.912 66.382 755.728 65.662 755.728 c
65.502 755.728 65.358 755.736 65.246 755.76 c
65.246 753.825 l
64.037 753.825 l
64.037 759.143 l
f
71.893 756.103 m
69.909 756.103 l
69.909 754.825 l
72.125 754.825 l
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68.694 753.825 l
68.694 759.216 l
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72.013 758.216 l
69.909 758.216 l
69.909 757.096 l
71.893 757.096 l
71.893 756.103 l
f
72.958 753.825 m
72.958 759.216 l
74.382 759.216 l
75.501 757.241 l
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77.421 759.216 l
77.421 753.825 l
76.141 753.825 l
74.989 755.905 l
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74.02 757.808 l
74.061 757.088 74.077 756.328 74.077 755.449 c
74.077 753.825 l
72.958 753.825 l
f
92.404 756.12 m
92.068 757.265 l
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91.78 758.305 l
91.709 757.984 91.62 757.577 91.541 757.265 c
91.213 756.12 l
92.404 756.12 l
h
91.037 755.207 m
90.66 753.825 l
89.397 753.825 l
91.045 759.216 l
92.636 759.216 l
94.316 753.825 l
93.005 753.825 l
92.589 755.207 l
91.037 755.207 l
f
98.789 753.975 m
98.573 753.871 98.061 753.745 97.414 753.745 c
95.548 753.745 94.589 754.912 94.589 756.449 c
94.589 758.281 95.901 759.296 97.533 759.296 c
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98.605 758.096 l
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96.621 758.296 95.87 757.712 95.87 756.512 c
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97.964 754.76 98.365 754.831 98.612 754.935 c
98.789 753.975 l
f
103.309 753.975 m
103.093 753.871 102.582 753.745 101.933 753.745 c
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103.125 758.096 l
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103.309 753.975 l
f
107.324 756.103 m
105.34 756.103 l
105.34 754.825 l
107.556 754.825 l
107.556 753.825 l
104.124 753.825 l
104.124 759.216 l
107.444 759.216 l
107.444 758.216 l
105.34 758.216 l
105.34 757.096 l
107.324 757.096 l
107.324 756.103 l
f
108.428 755.079 m
108.749 754.912 109.26 754.745 109.78 754.745 c
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111.388 758.048 l
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111.436 756.672 111.876 756.176 111.876 755.415 c
111.876 754.512 111.188 753.745 109.71 753.745 c
109.092 753.745 108.484 753.912 108.18 754.079 c
108.428 755.079 l
f
112.749 755.079 m
113.068 754.912 113.581 754.745 114.1 754.745 c
114.66 754.745 114.957 754.975 114.957 755.328 c
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116.196 754.512 115.508 753.745 114.028 753.745 c
113.413 753.745 112.804 753.912 112.501 754.079 c
112.749 755.079 l
f
120.268 759.216 m
123.556 759.216 l
123.556 758.216 l
121.484 758.216 l
121.484 756.984 l
123.42 756.984 l
123.42 755.993 l
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120.268 753.825 l
120.268 759.216 l
f
124.276 756.449 m
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125.284 757.736 l
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125.364 757.008 l
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126.676 756.656 l
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125.492 753.825 l
124.276 753.825 l
124.276 756.449 l
f
129.62 756.224 m
129.62 756.519 129.492 757.016 128.94 757.016 c
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129.62 756.224 l
h
128.188 755.392 m
128.228 754.888 128.724 754.648 129.292 754.648 c
129.708 754.648 130.044 754.704 130.372 754.816 c
130.532 753.993 l
130.132 753.825 129.643 753.745 129.116 753.745 c
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130.268 757.825 130.749 756.84 130.749 755.871 c
130.749 755.663 130.724 755.48 130.708 755.392 c
128.188 755.392 l
f
133.845 756.224 m
133.845 756.519 133.716 757.016 133.165 757.016 c
132.643 757.016 132.436 756.543 132.404 756.224 c
133.845 756.224 l
h
132.413 755.392 m
132.452 754.888 132.948 754.648 133.517 754.648 c
133.933 754.648 134.268 754.704 134.597 754.816 c
134.757 753.993 l
134.356 753.825 133.868 753.745 133.341 753.745 c
132.013 753.745 131.253 754.512 131.253 755.736 c
131.253 756.728 131.876 757.825 133.227 757.825 c
134.492 757.825 134.972 756.84 134.972 755.871 c
134.972 755.663 134.948 755.48 134.933 755.392 c
132.413 755.392 l
f
135.7 753.825 1.2158 5.6879 re
f
138.811 757.736 m
139.396 755.808 l
139.46 755.583 139.54 755.288 139.589 755.079 c
139.612 755.079 l
139.669 755.296 139.731 755.583 139.788 755.816 c
140.268 757.736 l
141.572 757.736 l
140.66 755.161 l
140.101 753.6 139.723 752.984 139.284 752.592 c
138.868 752.224 138.421 752.088 138.108 752.056 c
137.852 753.079 l
138.005 753.113 138.196 753.183 138.38 753.288 c
138.564 753.384 138.772 753.583 138.884 753.777 c
138.925 753.84 138.948 753.905 138.948 753.953 c
138.948 753.999 138.94 754.056 138.899 754.152 c
137.46 757.736 l
138.811 757.736 l
f
145.78 755.672 m
145.139 755.672 144.643 755.519 144.643 755.056 c
144.643 754.745 144.852 754.592 145.124 754.592 c
145.421 754.592 145.677 754.791 145.757 755.039 c
145.772 755.103 145.78 755.176 145.78 755.247 c
145.78 755.672 l
h
146.956 754.767 m
146.956 754.4 146.972 754.039 147.02 753.825 c
145.925 753.825 l
145.852 754.216 l
145.828 754.216 l
145.572 753.905 145.173 753.736 144.708 753.736 c
143.917 753.736 143.444 754.312 143.444 754.935 c
143.444 755.953 144.356 756.433 145.74 756.433 c
145.74 756.48 l
145.74 756.687 145.628 756.984 145.028 756.984 c
144.628 756.984 144.204 756.849 143.948 756.697 c
143.723 757.472 l
143.997 757.623 144.532 757.825 145.245 757.825 c
146.548 757.825 146.956 757.056 146.956 756.136 c
146.956 754.767 l
f
148.731 757.736 m
149.261 755.92 l
149.356 755.592 149.421 755.281 149.484 754.968 c
149.509 754.968 l
149.572 755.288 149.636 755.583 149.723 755.92 c
150.227 757.736 l
151.509 757.736 l
150.052 753.825 l
148.837 753.825 l
147.413 757.736 l
148.731 757.736 l
f
154.093 755.672 m
153.452 755.672 152.956 755.519 152.956 755.056 c
152.956 754.745 153.164 754.592 153.436 754.592 c
153.732 754.592 153.988 754.791 154.068 755.039 c
154.085 755.103 154.093 755.176 154.093 755.247 c
154.093 755.672 l
h
155.268 754.767 m
155.268 754.4 155.284 754.039 155.332 753.825 c
154.236 753.825 l
154.164 754.216 l
154.139 754.216 l
153.884 753.905 153.484 753.736 153.02 753.736 c
152.227 753.736 151.757 754.312 151.757 754.935 c
151.757 755.953 152.669 756.433 154.052 756.433 c
154.052 756.48 l
154.052 756.687 153.94 756.984 153.341 756.984 c
152.94 756.984 152.516 756.849 152.261 756.697 c
152.036 757.472 l
152.307 757.623 152.845 757.825 153.555 757.825 c
154.86 757.825 155.268 757.056 155.268 756.136 c
155.268 754.767 l
f
156.236 753.825 m
157.452 753.825 -1.2158 3.9121 re
156.236 753.825 m
h
156.837 758.216 m
156.452 758.216 156.204 758.489 156.204 758.825 c
156.204 759.167 156.46 759.432 156.852 759.432 c
157.245 759.432 157.484 759.167 157.492 758.825 c
157.492 758.489 157.245 758.216 156.844 758.216 c
156.837 758.216 l
f
158.428 753.825 1.215 5.6879 re
f
162.708 755.672 m
162.068 755.672 161.572 755.519 161.572 755.056 c
161.572 754.745 161.78 754.592 162.052 754.592 c
162.348 754.592 162.604 754.791 162.684 755.039 c
162.7 755.103 162.708 755.176 162.708 755.247 c
162.708 755.672 l
h
163.884 754.767 m
163.884 754.4 163.9 754.039 163.948 753.825 c
162.852 753.825 l
162.78 754.216 l
162.757 754.216 l
162.501 753.905 162.1 753.736 161.636 753.736 c
160.845 753.736 160.372 754.312 160.372 754.935 c
160.372 755.953 161.284 756.433 162.669 756.433 c
162.669 756.48 l
162.669 756.687 162.555 756.984 161.956 756.984 c
161.555 756.984 161.132 756.849 160.876 756.697 c
160.652 757.472 l
160.925 757.623 161.46 757.825 162.173 757.825 c
163.475 757.825 163.884 757.056 163.884 756.136 c
163.884 754.767 l
f
166.068 755.489 m
166.068 755.409 166.076 755.336 166.093 755.271 c
166.173 754.953 166.452 754.697 166.803 754.697 c
167.324 754.697 167.643 755.096 167.643 755.8 c
167.643 756.409 167.372 756.888 166.803 756.888 c
166.475 756.888 166.173 756.64 166.093 756.288 c
166.076 756.216 166.068 756.144 166.068 756.064 c
166.068 755.489 l
h
164.852 759.512 m
166.068 759.512 l
166.068 757.271 l
166.083 757.271 l
166.315 757.608 166.723 757.825 167.268 757.825 c
168.204 757.825 168.884 757.048 168.876 755.848 c
168.876 754.441 167.988 753.736 167.093 753.736 c
166.636 753.736 166.188 753.905 165.915 754.369 c
165.899 754.369 l
165.852 753.825 l
164.82 753.825 l
164.837 754.079 164.852 754.552 164.852 754.993 c
164.852 759.512 l
f
169.636 753.825 1.216 5.6879 re
f
174.204 756.224 m
174.204 756.519 174.076 757.016 173.522 757.016 c
173.003 757.016 172.796 756.543 172.764 756.224 c
174.204 756.224 l
h
172.771 755.392 m
172.811 754.888 173.307 754.648 173.876 754.648 c
174.292 754.648 174.628 754.704 174.956 754.816 c
175.116 753.993 l
174.716 753.825 174.227 753.745 173.7 753.745 c
172.372 753.745 171.612 754.512 171.612 755.736 c
171.612 756.728 172.236 757.825 173.587 757.825 c
174.852 757.825 175.333 756.84 175.333 755.871 c
175.333 755.663 175.307 755.48 175.292 755.392 c
172.771 755.392 l
f
179.509 754.609 m
179.988 754.609 180.284 755.079 180.284 755.785 c
180.284 756.361 180.059 756.953 179.509 756.953 c
178.932 756.953 178.708 756.361 178.708 755.777 c
178.708 755.113 178.988 754.609 179.501 754.609 c
179.509 754.609 l
h
179.475 753.736 m
178.333 753.736 177.452 754.489 177.452 755.751 c
177.452 757.016 178.284 757.825 179.548 757.825 c
180.74 757.825 181.54 756.999 181.54 755.816 c
181.54 754.392 180.524 753.736 179.484 753.736 c
179.475 753.736 l
f
182.292 756.489 m
182.292 756.976 182.276 757.384 182.261 757.736 c
183.316 757.736 l
183.372 757.193 l
183.395 757.193 l
183.555 757.449 183.948 757.825 184.602 757.825 c
185.404 757.825 186.003 757.288 186.003 756.136 c
186.003 753.825 l
184.788 753.825 l
184.788 755.993 l
184.788 756.496 184.612 756.84 184.173 756.84 c
183.835 756.84 183.636 756.609 183.548 756.384 c
183.516 756.304 183.509 756.193 183.509 756.079 c
183.509 753.825 l
182.292 753.825 l
182.292 756.489 l
f
186.979 753.825 1.217 5.6879 re
f
189.18 753.825 m
190.395 753.825 -1.215 3.9121 re
189.18 753.825 m
h
189.78 758.216 m
189.395 758.216 189.148 758.489 189.148 758.825 c
189.148 759.167 189.404 759.432 189.796 759.432 c
190.188 759.432 190.428 759.167 190.436 758.825 c
190.436 758.489 190.188 758.216 189.788 758.216 c
189.78 758.216 l
f
191.371 756.489 m
191.371 756.976 191.355 757.384 191.339 757.736 c
192.395 757.736 l
192.451 757.193 l
192.475 757.193 l
192.636 757.449 193.027 757.825 193.682 757.825 c
194.483 757.825 195.083 757.288 195.083 756.136 c
195.083 753.825 l
193.867 753.825 l
193.867 755.993 l
193.867 756.496 193.69 756.84 193.251 756.84 c
192.915 756.84 192.716 756.609 192.628 756.384 c
192.595 756.304 192.587 756.193 192.587 756.079 c
192.587 753.825 l
191.371 753.825 l
191.371 756.489 l
f
198.428 756.224 m
198.428 756.519 198.3 757.016 197.748 757.016 c
197.227 757.016 197.018 756.543 196.988 756.224 c
198.428 756.224 l
h
196.996 755.392 m
197.036 754.888 197.532 754.648 198.1 754.648 c
198.516 754.648 198.852 754.704 199.18 754.816 c
199.341 753.993 l
198.94 753.825 198.452 753.745 197.925 753.745 c
196.596 753.745 195.837 754.512 195.837 755.736 c
195.837 756.728 196.46 757.825 197.811 757.825 c
199.076 757.825 199.555 756.84 199.555 755.871 c
199.555 755.663 199.532 755.48 199.516 755.392 c
196.996 755.392 l
f
0.95686 0.3451 0.12549 0.02745 k
80.484 760.735 m
80.484 760.299 l
81.761 760.299 l
81.761 760.735 l
81.761 761.789 82.62 762.647 83.674 762.647 c
84.728 762.647 85.588 761.789 85.588 760.735 c
85.588 757.583 l
86.864 757.583 l
86.864 760.735 l
86.864 762.494 85.433 763.925 83.674 763.925 c
81.916 763.925 80.484 762.494 80.484 760.735 c
f
84.733 755.745 m
84.733 755.161 84.261 754.689 83.679 754.689 c
83.097 754.689 82.626 755.161 82.626 755.745 c
82.626 756.327 83.097 756.798 83.679 756.798 c
84.261 756.798 84.733 756.327 84.733 755.745 c
f
81.183 755.755 m
81.183 757.125 82.298 758.24 83.668 758.24 c
85.037 758.24 86.151 757.125 86.151 755.755 c
86.151 754.385 85.037 753.271 83.668 753.271 c
82.298 753.271 81.183 754.385 81.183 755.755 c
h
79.906 755.755 m
79.906 753.68 81.592 751.994 83.668 751.994 c
85.741 751.994 87.429 753.68 87.429 755.755 c
87.429 757.829 85.741 759.517 83.668 759.517 c
81.592 759.517 79.906 757.829 79.906 755.755 c
f
60.654 754.704 m
61.477 754.704 61.95 755.48 61.95 756.536 c
61.95 757.504 61.493 758.335 60.654 758.335 c
59.813 758.335 59.342 757.519 59.342 756.512 c
59.342 755.496 59.83 754.704 60.645 754.704 c
60.654 754.704 l
h
60.59 753.736 m
58.998 753.736 58.054 754.945 58.054 756.48 c
58.054 758.096 59.094 759.304 60.678 759.304 c
62.334 759.304 63.238 758.063 63.238 756.577 c
63.238 754.8 62.174 753.736 60.597 753.736 c
60.59 753.736 l
f
65.246 756.697 m
65.349 756.672 65.47 756.663 65.654 756.663 c
66.302 756.663 66.701 756.993 66.701 757.536 c
66.701 758.033 66.358 758.328 65.741 758.328 c
65.502 758.328 65.332 758.311 65.246 758.288 c
65.246 756.697 l
h
64.037 759.143 m
64.414 759.207 64.942 759.256 65.686 759.256 c
66.436 759.256 66.973 759.113 67.333 758.816 c
67.685 758.552 67.909 758.103 67.909 757.577 c
67.909 757.039 67.741 756.592 67.414 756.296 c
66.998 755.912 66.382 755.728 65.662 755.728 c
65.502 755.728 65.358 755.736 65.246 755.76 c
65.246 753.825 l
64.037 753.825 l
64.037 759.143 l
f
71.893 756.103 m
69.909 756.103 l
69.909 754.825 l
72.125 754.825 l
72.125 753.825 l
68.694 753.825 l
68.694 759.216 l
72.013 759.216 l
72.013 758.216 l
69.909 758.216 l
69.909 757.096 l
71.893 757.096 l
71.893 756.103 l
f
72.958 753.825 m
72.958 759.216 l
74.382 759.216 l
75.501 757.241 l
75.822 756.672 76.134 755.999 76.382 755.392 c
76.397 755.392 l
76.326 756.103 76.301 756.831 76.301 757.647 c
76.301 759.216 l
77.421 759.216 l
77.421 753.825 l
76.141 753.825 l
74.989 755.905 l
74.669 756.489 74.309 757.176 74.053 757.808 c
74.02 757.808 l
74.061 757.088 74.077 756.328 74.077 755.449 c
74.077 753.825 l
72.958 753.825 l
f
92.404 756.12 m
92.068 757.265 l
91.981 757.583 91.884 757.993 91.804 758.305 c
91.78 758.305 l
91.709 757.984 91.62 757.577 91.541 757.265 c
91.213 756.12 l
92.404 756.12 l
h
91.037 755.207 m
90.66 753.825 l
89.397 753.825 l
91.045 759.216 l
92.636 759.216 l
94.316 753.825 l
93.005 753.825 l
92.589 755.207 l
91.037 755.207 l
f
98.789 753.975 m
98.573 753.871 98.061 753.745 97.414 753.745 c
95.548 753.745 94.589 754.912 94.589 756.449 c
94.589 758.281 95.901 759.296 97.533 759.296 c
98.166 759.296 98.644 759.167 98.86 759.063 c
98.605 758.096 l
98.365 758.201 98.02 758.296 97.582 758.296 c
96.621 758.296 95.87 757.712 95.87 756.512 c
95.87 755.441 96.509 754.76 97.589 754.76 c
97.964 754.76 98.365 754.831 98.612 754.935 c
98.789 753.975 l
f
103.309 753.975 m
103.093 753.871 102.582 753.745 101.933 753.745 c
100.068 753.745 99.109 754.912 99.109 756.449 c
99.109 758.281 100.421 759.296 102.053 759.296 c
102.686 759.296 103.166 759.167 103.38 759.063 c
103.125 758.096 l
102.885 758.201 102.541 758.296 102.101 758.296 c
101.141 758.296 100.389 757.712 100.389 756.512 c
100.389 755.441 101.029 754.76 102.109 754.76 c
102.484 754.76 102.885 754.831 103.132 754.935 c
103.309 753.975 l
f
107.324 756.103 m
105.34 756.103 l
105.34 754.825 l
107.556 754.825 l
107.556 753.825 l
104.124 753.825 l
104.124 759.216 l
107.444 759.216 l
107.444 758.216 l
105.34 758.216 l
105.34 757.096 l
107.324 757.096 l
107.324 756.103 l
f
108.428 755.079 m
108.749 754.912 109.26 754.745 109.78 754.745 c
110.34 754.745 110.636 754.975 110.636 755.328 c
110.636 755.663 110.38 755.857 109.732 756.079 c
108.836 756.4 108.245 756.896 108.245 757.681 c
108.245 758.6 109.02 759.296 110.284 759.296 c
110.9 759.296 111.34 759.176 111.66 759.023 c
111.388 758.048 l
111.18 758.152 110.789 758.305 110.268 758.305 c
109.74 758.305 109.484 758.056 109.484 757.785 c
109.484 757.441 109.78 757.288 110.484 757.025 c
111.436 756.672 111.876 756.176 111.876 755.415 c
111.876 754.512 111.188 753.745 109.71 753.745 c
109.092 753.745 108.484 753.912 108.18 754.079 c
108.428 755.079 l
f
112.749 755.079 m
113.068 754.912 113.581 754.745 114.1 754.745 c
114.66 754.745 114.957 754.975 114.957 755.328 c
114.957 755.663 114.7 755.857 114.052 756.079 c
113.156 756.4 112.564 756.896 112.564 757.681 c
112.564 758.6 113.34 759.296 114.604 759.296 c
115.22 759.296 115.66 759.176 115.98 759.023 c
115.709 758.048 l
115.501 758.152 115.108 758.305 114.588 758.305 c
114.06 758.305 113.804 758.056 113.804 757.785 c
113.804 757.441 114.1 757.288 114.804 757.025 c
115.756 756.672 116.196 756.176 116.196 755.415 c
116.196 754.512 115.508 753.745 114.028 753.745 c
113.413 753.745 112.804 753.912 112.501 754.079 c
112.749 755.079 l
f
120.268 759.216 m
123.556 759.216 l
123.556 758.216 l
121.484 758.216 l
121.484 756.984 l
123.42 756.984 l
123.42 755.993 l
121.484 755.993 l
121.484 753.825 l
120.268 753.825 l
120.268 759.216 l
f
124.276 756.449 m
124.276 757.025 124.268 757.4 124.245 757.736 c
125.284 757.736 l
125.332 757.008 l
125.364 757.008 l
125.564 757.583 126.037 757.825 126.42 757.825 c
126.532 757.825 126.588 757.816 126.676 757.8 c
126.676 756.656 l
126.58 756.672 126.484 756.687 126.348 756.687 c
125.9 756.687 125.596 756.455 125.516 756.073 c
125.5 755.993 125.492 755.905 125.492 755.8 c
125.492 753.825 l
124.276 753.825 l
124.276 756.449 l
f
129.62 756.224 m
129.62 756.519 129.492 757.016 128.94 757.016 c
128.42 757.016 128.212 756.543 128.18 756.224 c
129.62 756.224 l
h
128.188 755.392 m
128.228 754.888 128.724 754.648 129.292 754.648 c
129.708 754.648 130.044 754.704 130.372 754.816 c
130.532 753.993 l
130.132 753.825 129.643 753.745 129.116 753.745 c
127.789 753.745 127.028 754.512 127.028 755.736 c
127.028 756.728 127.652 757.825 129.005 757.825 c
130.268 757.825 130.749 756.84 130.749 755.871 c
130.749 755.663 130.724 755.48 130.708 755.392 c
128.188 755.392 l
f
133.845 756.224 m
133.845 756.519 133.716 757.016 133.165 757.016 c
132.643 757.016 132.436 756.543 132.404 756.224 c
133.845 756.224 l
h
132.413 755.392 m
132.452 754.888 132.948 754.648 133.517 754.648 c
133.933 754.648 134.268 754.704 134.597 754.816 c
134.757 753.993 l
134.356 753.825 133.868 753.745 133.341 753.745 c
132.013 753.745 131.253 754.512 131.253 755.736 c
131.253 756.728 131.876 757.825 133.227 757.825 c
134.492 757.825 134.972 756.84 134.972 755.871 c
134.972 755.663 134.948 755.48 134.933 755.392 c
132.413 755.392 l
f
135.7 753.825 1.2158 5.6879 re
f
138.811 757.736 m
139.396 755.808 l
139.46 755.583 139.54 755.288 139.589 755.079 c
139.612 755.079 l
139.669 755.296 139.731 755.583 139.788 755.816 c
140.268 757.736 l
141.572 757.736 l
140.66 755.161 l
140.101 753.6 139.723 752.984 139.284 752.592 c
138.868 752.224 138.421 752.088 138.108 752.056 c
137.852 753.079 l
138.005 753.113 138.196 753.183 138.38 753.288 c
138.564 753.384 138.772 753.583 138.884 753.777 c
138.925 753.84 138.948 753.905 138.948 753.953 c
138.948 753.999 138.94 754.056 138.899 754.152 c
137.46 757.736 l
138.811 757.736 l
f
145.78 755.672 m
145.139 755.672 144.643 755.519 144.643 755.056 c
144.643 754.745 144.852 754.592 145.124 754.592 c
145.421 754.592 145.677 754.791 145.757 755.039 c
145.772 755.103 145.78 755.176 145.78 755.247 c
145.78 755.672 l
h
146.956 754.767 m
146.956 754.4 146.972 754.039 147.02 753.825 c
145.925 753.825 l
145.852 754.216 l
145.828 754.216 l
145.572 753.905 145.173 753.736 144.708 753.736 c
143.917 753.736 143.444 754.312 143.444 754.935 c
143.444 755.953 144.356 756.433 145.74 756.433 c
145.74 756.48 l
145.74 756.687 145.628 756.984 145.028 756.984 c
144.628 756.984 144.204 756.849 143.948 756.697 c
143.723 757.472 l
143.997 757.623 144.532 757.825 145.245 757.825 c
146.548 757.825 146.956 757.056 146.956 756.136 c
146.956 754.767 l
f
148.731 757.736 m
149.261 755.92 l
149.356 755.592 149.421 755.281 149.484 754.968 c
149.509 754.968 l
149.572 755.288 149.636 755.583 149.723 755.92 c
150.227 757.736 l
151.509 757.736 l
150.052 753.825 l
148.837 753.825 l
147.413 757.736 l
148.731 757.736 l
f
154.093 755.672 m
153.452 755.672 152.956 755.519 152.956 755.056 c
152.956 754.745 153.164 754.592 153.436 754.592 c
153.732 754.592 153.988 754.791 154.068 755.039 c
154.085 755.103 154.093 755.176 154.093 755.247 c
154.093 755.672 l
h
155.268 754.767 m
155.268 754.4 155.284 754.039 155.332 753.825 c
154.236 753.825 l
154.164 754.216 l
154.139 754.216 l
153.884 753.905 153.484 753.736 153.02 753.736 c
152.227 753.736 151.757 754.312 151.757 754.935 c
151.757 755.953 152.669 756.433 154.052 756.433 c
154.052 756.48 l
154.052 756.687 153.94 756.984 153.341 756.984 c
152.94 756.984 152.516 756.849 152.261 756.697 c
152.036 757.472 l
152.307 757.623 152.845 757.825 153.555 757.825 c
154.86 757.825 155.268 757.056 155.268 756.136 c
155.268 754.767 l
f
156.236 753.825 m
157.452 753.825 -1.2158 3.9121 re
156.236 753.825 m
h
156.837 758.216 m
156.452 758.216 156.204 758.489 156.204 758.825 c
156.204 759.167 156.46 759.432 156.852 759.432 c
157.245 759.432 157.484 759.167 157.492 758.825 c
157.492 758.489 157.245 758.216 156.844 758.216 c
156.837 758.216 l
f
158.428 753.825 1.215 5.6879 re
f
162.708 755.672 m
162.068 755.672 161.572 755.519 161.572 755.056 c
161.572 754.745 161.78 754.592 162.052 754.592 c
162.348 754.592 162.604 754.791 162.684 755.039 c
162.7 755.103 162.708 755.176 162.708 755.247 c
162.708 755.672 l
h
163.884 754.767 m
163.884 754.4 163.9 754.039 163.948 753.825 c
162.852 753.825 l
162.78 754.216 l
162.757 754.216 l
162.501 753.905 162.1 753.736 161.636 753.736 c
160.845 753.736 160.372 754.312 160.372 754.935 c
160.372 755.953 161.284 756.433 162.669 756.433 c
162.669 756.48 l
162.669 756.687 162.555 756.984 161.956 756.984 c
161.555 756.984 161.132 756.849 160.876 756.697 c
160.652 757.472 l
160.925 757.623 161.46 757.825 162.173 757.825 c
163.475 757.825 163.884 757.056 163.884 756.136 c
163.884 754.767 l
f
166.068 755.489 m
166.068 755.409 166.076 755.336 166.093 755.271 c
166.173 754.953 166.452 754.697 166.803 754.697 c
167.324 754.697 167.643 755.096 167.643 755.8 c
167.643 756.409 167.372 756.888 166.803 756.888 c
166.475 756.888 166.173 756.64 166.093 756.288 c
166.076 756.216 166.068 756.144 166.068 756.064 c
166.068 755.489 l
h
164.852 759.512 m
166.068 759.512 l
166.068 757.271 l
166.083 757.271 l
166.315 757.608 166.723 757.825 167.268 757.825 c
168.204 757.825 168.884 757.048 168.876 755.848 c
168.876 754.441 167.988 753.736 167.093 753.736 c
166.636 753.736 166.188 753.905 165.915 754.369 c
165.899 754.369 l
165.852 753.825 l
164.82 753.825 l
164.837 754.079 164.852 754.552 164.852 754.993 c
164.852 759.512 l
f
169.636 753.825 1.216 5.6879 re
f
174.204 756.224 m
174.204 756.519 174.076 757.016 173.522 757.016 c
173.003 757.016 172.796 756.543 172.764 756.224 c
174.204 756.224 l
h
172.771 755.392 m
172.811 754.888 173.307 754.648 173.876 754.648 c
174.292 754.648 174.628 754.704 174.956 754.816 c
175.116 753.993 l
174.716 753.825 174.227 753.745 173.7 753.745 c
172.372 753.745 171.612 754.512 171.612 755.736 c
171.612 756.728 172.236 757.825 173.587 757.825 c
174.852 757.825 175.333 756.84 175.333 755.871 c
175.333 755.663 175.307 755.48 175.292 755.392 c
172.771 755.392 l
f
179.509 754.609 m
179.988 754.609 180.284 755.079 180.284 755.785 c
180.284 756.361 180.059 756.953 179.509 756.953 c
178.932 756.953 178.708 756.361 178.708 755.777 c
178.708 755.113 178.988 754.609 179.501 754.609 c
179.509 754.609 l
h
179.475 753.736 m
178.333 753.736 177.452 754.489 177.452 755.751 c
177.452 757.016 178.284 757.825 179.548 757.825 c
180.74 757.825 181.54 756.999 181.54 755.816 c
181.54 754.392 180.524 753.736 179.484 753.736 c
179.475 753.736 l
f
182.292 756.489 m
182.292 756.976 182.276 757.384 182.261 757.736 c
183.316 757.736 l
183.372 757.193 l
183.395 757.193 l
183.555 757.449 183.948 757.825 184.602 757.825 c
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186.003 753.825 l
184.788 753.825 l
184.788 755.993 l
184.788 756.496 184.612 756.84 184.173 756.84 c
183.835 756.84 183.636 756.609 183.548 756.384 c
183.516 756.304 183.509 756.193 183.509 756.079 c
183.509 753.825 l
182.292 753.825 l
182.292 756.489 l
f
186.979 753.825 1.217 5.6879 re
f
189.18 753.825 m
190.395 753.825 -1.215 3.9121 re
189.18 753.825 m
h
189.78 758.216 m
189.395 758.216 189.148 758.489 189.148 758.825 c
189.148 759.167 189.404 759.432 189.796 759.432 c
190.188 759.432 190.428 759.167 190.436 758.825 c
190.436 758.489 190.188 758.216 189.788 758.216 c
189.78 758.216 l
f
191.371 756.489 m
191.371 756.976 191.355 757.384 191.339 757.736 c
192.395 757.736 l
192.451 757.193 l
192.475 757.193 l
192.636 757.449 193.027 757.825 193.682 757.825 c
194.483 757.825 195.083 757.288 195.083 756.136 c
195.083 753.825 l
193.867 753.825 l
193.867 755.993 l
193.867 756.496 193.69 756.84 193.251 756.84 c
192.915 756.84 192.716 756.609 192.628 756.384 c
192.595 756.304 192.587 756.193 192.587 756.079 c
192.587 753.825 l
191.371 753.825 l
191.371 756.489 l
f
198.428 756.224 m
198.428 756.519 198.3 757.016 197.748 757.016 c
197.227 757.016 197.018 756.543 196.988 756.224 c
198.428 756.224 l
h
196.996 755.392 m
197.036 754.888 197.532 754.648 198.1 754.648 c
198.516 754.648 198.852 754.704 199.18 754.816 c
199.341 753.993 l
198.94 753.825 198.452 753.745 197.925 753.745 c
196.596 753.745 195.837 754.512 195.837 755.736 c
195.837 756.728 196.46 757.825 197.811 757.825 c
199.076 757.825 199.555 756.84 199.555 755.871 c
199.555 755.663 199.532 755.48 199.516 755.392 c
196.996 755.392 l
f
/Document /MC1 BDC
0.2 0 0.2 0.65 k
429.829 757.842 m
430.078 757.828 430.341 757.783 430.591 757.783 c
431.949 757.783 432.617 758.44 432.617 760.051 c
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430.579 762.245 430.052 762.245 429.921 762.154 c
429.818 762.08 429.829 761.916 429.829 761.543 c
429.829 757.842 l
h
429.829 755.634 m
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427.238 762.677 l
427.908 762.663 430.163 762.713 431.105 762.677 c
432.527 762.622 434.13 761.991 434.13 760.096 c
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429.829 755.634 l
f
435.878 759.843 m
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435.035 753.144 435.576 753.144 435.745 753.649 c
435.878 754.054 435.878 755.157 435.878 755.634 c
435.878 759.843 l
f
q
427.238 762.856 126.562 -10.314 re
W
n
442.995 758.124 m
442.995 756.706 443.365 755.063 444.902 755.063 c
446.339 755.063 446.693 756.706 446.693 758.035 c
446.693 759.466 446.339 761.138 444.785 761.138 c
443.351 761.138 442.995 759.422 442.995 758.124 c
h
448.007 758.124 m
448.007 756.108 446.562 754.722 444.835 754.722 c
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441.681 760.093 443.234 761.481 444.835 761.481 c
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f
448.808 755.593 m
449.124 755.593 l
449.386 754.087 450.152 752.888 451.663 752.888 c
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454.113 762.677 l
454.177 760.096 l
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453.572 761.333 452.952 762.453 451.677 762.453 c
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450.743 752.483 450.046 752.78 449.337 753.38 c
449.081 752.655 l
448.937 752.655 l
448.808 755.593 l
f
Q
0.42 0.08 0 0.4 k
461.356 752.778 m
461.14 752.675 460.628 752.546 459.98 752.546 c
458.116 752.546 457.156 753.714 457.156 755.259 c
457.156 757.098 458.468 758.114 460.1 758.114 c
460.732 758.114 461.212 757.986 461.428 757.874 c
461.172 756.914 l
460.932 757.019 460.588 757.114 460.148 757.114 c
459.188 757.114 458.436 756.53 458.436 755.322 c
458.436 754.242 459.076 753.563 460.156 753.563 c
460.532 753.563 460.932 753.634 461.18 753.738 c
461.356 752.778 l
f
464.262 753.515 m
465.086 753.515 465.558 754.29 465.558 755.347 c
465.558 756.314 465.102 757.146 464.262 757.146 c
463.422 757.146 462.949 756.33 462.949 755.322 c
462.949 754.306 463.438 753.515 464.254 753.515 c
464.262 753.515 l
h
464.206 752.546 m
462.614 752.546 461.67 753.755 461.67 755.29 c
461.67 756.906 462.71 758.114 464.294 758.114 c
465.949 758.114 466.854 756.874 466.854 755.386 c
466.854 753.61 465.79 752.546 464.214 752.546 c
464.206 752.546 l
f
472.214 754.698 m
472.19 755.347 472.166 756.122 472.166 756.914 c
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471.974 756.226 471.75 755.458 471.542 754.826 c
470.886 752.722 l
469.934 752.722 l
469.359 754.802 l
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468.854 756.914 l
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468.662 752.634 l
467.534 752.634 l
467.878 758.026 l
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470.03 756.218 l
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471.598 758.026 l
473.198 758.026 l
473.486 752.634 l
472.302 752.634 l
472.214 754.698 l
f
475.63 755.507 m
475.734 755.482 475.861 755.474 476.037 755.474 c
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477.086 756.843 476.749 757.138 476.134 757.138 c
475.886 757.138 475.718 757.122 475.63 757.098 c
475.63 755.507 l
h
474.422 757.954 m
474.798 758.018 475.325 758.066 476.069 758.066 c
476.821 758.066 477.365 757.922 477.726 757.626 c
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475.63 752.634 l
474.422 752.634 l
474.422 757.954 l
f
480.286 758.026 m
480.286 754.931 l
480.286 753.994 480.646 753.522 481.262 753.522 c
481.902 753.522 482.254 753.97 482.254 754.931 c
482.254 758.026 l
483.47 758.026 l
483.47 755.003 l
483.47 753.339 482.63 752.546 481.222 752.546 c
479.862 752.546 479.07 753.306 479.07 755.019 c
479.07 758.026 l
480.286 758.026 l
f
485.573 757.003 m
484.117 757.003 l
484.117 758.026 l
488.261 758.026 l
488.261 757.003 l
486.789 757.003 l
486.789 752.634 l
485.573 752.634 l
485.573 757.003 l
f
490.951 754.931 m
490.615 756.074 l
490.527 756.394 490.432 756.802 490.352 757.114 c
490.327 757.114 l
490.256 756.794 490.168 756.386 490.088 756.074 c
489.76 754.931 l
490.951 754.931 l
h
489.584 754.019 m
489.208 752.634 l
487.943 752.634 l
489.592 758.026 l
491.184 758.026 l
492.863 752.634 l
491.552 752.634 l
491.136 754.019 l
489.584 754.019 l
f
493.913 757.003 m
492.457 757.003 l
492.457 758.026 l
496.601 758.026 l
496.601 757.003 l
495.129 757.003 l
495.129 752.634 l
493.913 752.634 l
493.913 757.003 l
f
497.257 752.634 1.2159 5.3926 re
f
501.872 753.515 m
502.696 753.515 503.168 754.29 503.168 755.347 c
503.168 756.314 502.712 757.146 501.872 757.146 c
501.032 757.146 500.56 756.33 500.56 755.322 c
500.56 754.306 501.048 753.515 501.864 753.515 c
501.872 753.515 l
h
501.816 752.546 m
500.224 752.546 499.28 753.755 499.28 755.29 c
499.28 756.906 500.32 758.114 501.904 758.114 c
503.56 758.114 504.464 756.874 504.464 755.386 c
504.464 753.61 503.4 752.546 501.824 752.546 c
501.816 752.546 l
f
505.265 752.634 m
505.265 758.026 l
506.688 758.026 l
507.809 756.05 l
508.128 755.482 508.44 754.81 508.688 754.202 c
508.704 754.202 l
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508.608 758.026 l
509.728 758.026 l
509.728 752.634 l
508.448 752.634 l
507.296 754.714 l
506.977 755.298 506.616 755.986 506.36 756.618 c
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506.368 755.898 506.385 755.138 506.385 754.259 c
506.385 752.634 l
505.265 752.634 l
f
513.399 754.931 m
513.063 756.074 l
512.976 756.394 512.88 756.802 512.8 757.114 c
512.775 757.114 l
512.704 756.794 512.616 756.386 512.536 756.074 c
512.208 754.931 l
513.399 754.931 l
h
512.032 754.019 m
511.656 752.634 l
510.392 752.634 l
512.04 758.026 l
513.632 758.026 l
515.311 752.634 l
514 752.634 l
513.584 754.019 l
512.032 754.019 l
f
516.04 758.026 m
517.256 758.026 l
517.256 753.658 l
519.399 753.658 l
519.399 752.634 l
516.04 752.634 l
516.04 758.026 l
f
522.944 753.498 m
523.064 753.474 523.208 753.474 523.416 753.474 c
523.968 753.474 524.456 753.69 524.456 754.259 c
524.456 754.802 523.968 755.019 523.36 755.019 c
522.944 755.019 l
522.944 753.498 l
h
522.944 755.89 m
523.344 755.89 l
523.992 755.89 524.328 756.154 524.328 756.554 c
524.328 756.962 524.016 757.178 523.464 757.178 c
523.192 757.178 523.04 757.162 522.944 757.138 c
522.944 755.89 l
h
521.736 757.946 m
522.056 758.01 522.696 758.066 523.311 758.066 c
524.056 758.066 524.512 757.994 524.904 757.762 c
525.28 757.562 525.544 757.194 525.544 756.698 c
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524.664 755.538 l
525.28 755.378 525.736 754.906 525.736 754.21 c
525.736 753.714 525.512 753.33 525.176 753.066 c
524.784 752.755 524.128 752.578 523.056 752.578 c
522.456 752.578 522.008 752.618 521.736 752.658 c
521.736 757.946 l
f
526.576 752.634 1.2161 5.3926 re
f
531.191 753.515 m
532.015 753.515 532.487 754.29 532.487 755.347 c
532.487 756.314 532.031 757.146 531.191 757.146 c
530.351 757.146 529.879 756.33 529.879 755.322 c
529.879 754.306 530.367 753.515 531.183 753.515 c
531.191 753.515 l
h
531.135 752.546 m
529.543 752.546 528.599 753.755 528.599 755.29 c
528.599 756.906 529.639 758.114 531.223 758.114 c
532.879 758.114 533.783 756.874 533.783 755.386 c
533.783 753.61 532.719 752.546 531.143 752.546 c
531.135 752.546 l
f
534.591 758.026 m
535.807 758.026 l
535.807 753.658 l
537.951 753.658 l
537.951 752.634 l
534.591 752.634 l
534.591 758.026 l
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