Sendi, Parham; Proctor, Richard A (2009). Staphylococcus aureus as an intracellular pathogen: the role of small colony variants. Trends in microbiology, 17(2), pp. 54-8. Cambridge: Elsevier Current Trends 10.1016/j.tim.2008.11.004
Full text not available from this repository.Increasing evidence indicates that Staphylococcus aureus might be a facultative intracellular pathogen. In particular, certain subpopulations, called small colony variants (SCVs), seem to be well adapted to the intracellular milieu. When compared to 'normal' staphylococcal strains, SCVs show increased uptake by host cells, resistance to intracellular defenses and reduced stimulation of host defenses. We propose that the ability to form two subpopulations with different phenotypes might allow S. aureus the option for both extra- cellular and intra-cellular survival in the host.
Item Type: |
Journal Article (Further Contribution) |
|---|---|
Division/Institute: |
04 Faculty of Medicine > Department of Haematology, Oncology, Infectious Diseases, Laboratory Medicine and Hospital Pharmacy (DOLS) > Clinic of Infectiology |
UniBE Contributor: |
Sendi, Parham |
ISSN: |
0966-842X |
Publisher: |
Elsevier Current Trends |
Language: |
English |
Submitter: |
Factscience Import |
Date Deposited: |
04 Oct 2013 15:14 |
Last Modified: |
05 Dec 2022 14:22 |
Publisher DOI: |
10.1016/j.tim.2008.11.004 |
PubMed ID: |
19162480 |
Web of Science ID: |
000264279200002 |
URI: |
https://boris.unibe.ch/id/eprint/32465 (FactScience: 197673) |
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