Hemispheric lateralization of the corticostriatal glutamatergic system in the rat

Capper-Loup, Christine; Rebell, Dominik; Kaelin-Lang, Alain (2009). Hemispheric lateralization of the corticostriatal glutamatergic system in the rat. Journal of neural transmission, 116(9), pp. 1053-7. Wien: Springer Vienna 10.1007/s00702-009-0265-2

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Little is known about hemispheric lateralization of subcortical structures. Here, we show a higher expression of the subunit NR2A of the NMDA receptor mRNA in the striatum and of vGluT1 mRNA in the cingulate cortex, in the left hemisphere compared to the right one. This suggests a lateralization of the glutamatergic cortico-subcortical system, at the level of postsynaptic receptors as well as at the level of corticostriatal projections. Such lateralization could play a role in asymmetric diseases like Parkinson's disease.

Item Type:

Journal Article (Original Article)

Division/Institute:

04 Faculty of Medicine > Department of Head Organs and Neurology (DKNS) > Clinic of Neurology

UniBE Contributor:

Kaelin, Alain

ISSN:

0300-9564

Publisher:

Springer Vienna

Language:

English

Submitter:

Factscience Import

Date Deposited:

04 Oct 2013 15:14

Last Modified:

24 Oct 2019 11:18

Publisher DOI:

10.1007/s00702-009-0265-2

PubMed ID:

19626270

Web of Science ID:

000269320600001

BORIS DOI:

10.7892/boris.32626

URI:

https://boris.unibe.ch/id/eprint/32626 (FactScience: 197872)

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