When do combinations of diuretics make sense?

Fuster, Daniel Guido (2009). When do combinations of diuretics make sense? Therapeutische Umschau, 66(11), pp. 725-9. Bern: Huber 10.1024/0040-5930.66.11.725

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Diuretics are commonly prescribed by physicians to contract the ECF volume. In two clinical situations combining different classes of diuretics make sense: First, if a loop diuretic at maximal dose alone does not lead to sufficient diuresis or second, if the side effect of a diuretic needs to be corrected by adding a diuretic of another class. The latter is clinically often used to counteract loop or thiazide diuretic-induced hypokalemia by the addition of a potassium sparing diuretic. Key to a reasonable combination of diuretics is understanding of the pharmaco-kinetics and knowledge of the molecular targets of the diuretics involved.

Item Type:

Journal Article (Further Contribution)

Division/Institute:

04 Faculty of Medicine > Department of Dermatology, Urology, Rheumatology, Nephrology, Osteoporosis (DURN) > Clinic of Nephrology and Hypertension

UniBE Contributor:

Fuster, Daniel Guido

Subjects:

600 Technology > 610 Medicine & health

ISSN:

0040-5930

Publisher:

Huber

Language:

German

Submitter:

Factscience Import

Date Deposited:

04 Oct 2013 15:14

Last Modified:

11 Sep 2017 19:04

Publisher DOI:

10.1024/0040-5930.66.11.725

PubMed ID:

19885788

BORIS DOI:

10.7892/boris.32700

URI:

https://boris.unibe.ch/id/eprint/32700 (FactScience: 198000)

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