Glucocorticoid treatment, immobility, and constipation are associated with nutritional risk

Gutzwiller, Jean-Pierre; Aschwanden, Josef; Iff, Samuel; Leuenberger, Michèle; Perrig, Martin; Stanga, Zeno (2011). Glucocorticoid treatment, immobility, and constipation are associated with nutritional risk. European Journal of Nutrition, 50(8), pp. 665-671. Heidelberg: Springer-Verlag 10.1007/s00394-011-0177-4

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Purpose

The hypothesis of this clinical study was to determine whether glucocorticoid use and immobility were associated with in-hospital nutritional risk.

Methods

One hundred and one patients consecutively admitted to the medical wards were enrolled. Current medical conditions, symptoms, medical history, eating and drinking habits, diagnosis, laboratory findings, medications, and anthropometrics were recorded. The Nutrition Risk Score 2002 (NRS-2002) was used as a screening instrument to identify nutritional risk.

Results

The results confirmed that glucocorticoid use and immobility are independently associated with nutritional risk determined by the NRS-2002. Constipation could be determined as an additional cofactor independently associated with nutritional risk.

Conclusions

Glucocorticoid treatment, immobility, and constipation are associated with nutritional risk in a mixed hospitalized population. The presence of long-time glucocorticoid use, immobility, or constipation should alert the clinician to check for nutritional status, which is an important factor in mortality and morbidity.

Item Type:

Journal Article (Original Article)

Division/Institute:

04 Faculty of Medicine > Department of Gynaecology, Paediatrics and Endocrinology (DFKE) > Clinic of Endocrinology, Diabetology and Clinical Nutrition
04 Faculty of Medicine > Pre-clinic Human Medicine > Institute of Social and Preventive Medicine (ISPM)
04 Faculty of Medicine > Department of General Internal Medicine (DAIM) > Clinic of General Internal Medicine > Centre of Competence for General Internal Medicine

UniBE Contributor:

Iff, Samuel; Leuenberger, Michèle Simone; Perrig, Martin and Stanga-Nodari, Zeno

Subjects:

600 Technology > 610 Medicine & health

ISSN:

1436-6207

Publisher:

Springer-Verlag

Language:

English

Submitter:

Factscience Import

Date Deposited:

04 Oct 2013 14:14

Last Modified:

01 Oct 2020 13:35

Publisher DOI:

10.1007/s00394-011-0177-4

PubMed ID:

21369745

Web of Science ID:

000297129700007

BORIS DOI:

10.7892/boris.3470

URI:

https://boris.unibe.ch/id/eprint/3470 (FactScience: 207267)

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