An optical coherence tomography study of a biodegradable vs. durable polymer-coated limus-eluting stent: a LEADERS trial sub-study

Barlis, Peter; Regar, Evelyn; Serruys, Patrick W; Dimopoulos, Konstantinos; van der Giessen, Willem J; van Geuns, Robert-Jan M; Ferrante, Giuseppe; Wandel, Simon; Windecker, Stephan; van Es, Gerrit-Anne; Eerdmans, Pedro; Jüni, Peter; di Mario, Carlo (2010). An optical coherence tomography study of a biodegradable vs. durable polymer-coated limus-eluting stent: a LEADERS trial sub-study. European Heart Journal, 31(2), pp. 165-176. Oxford: Oxford University Press 10.1093/eurheartj/ehp480

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Incomplete endothelialization has been found to be associated with late stent thrombosis, a rare but devastating phenomenon, more frequent after drug-eluting stent implantation. Optical coherence tomography (OCT) has 10 times greater resolution than intravascular ultrasound and thus appears to be a valuable modality for the assessment of stent strut coverage. The LEADERS trial was a multi-centre, randomized comparison of a biolimus-eluting stent (BES) with biodegradable polymer with a sirolimus-eluting stent (SES) using a durable polymer. This study sought to evaluate tissue coverage and apposition of stents using OCT in a group of patients from the randomized LEADERS trial.

Item Type:

Journal Article (Original Article)

Division/Institute:

04 Faculty of Medicine > Pre-clinic Human Medicine > Institute of Social and Preventive Medicine
04 Faculty of Medicine > Department of Cardiovascular Disorders (DHGE) > Clinic of Cardiology

UniBE Contributor:

Wandel, Simon; Windecker, Stephan and Jüni, Peter

Subjects:

600 Technology > 610 Medicine & health
300 Social sciences, sociology & anthropology > 360 Social problems & social services

ISSN:

0195-668X

Publisher:

Oxford University Press

Language:

English

Submitter:

Factscience Import

Date Deposited:

04 Oct 2013 14:07

Last Modified:

22 Oct 2019 21:54

Publisher DOI:

10.1093/eurheartj/ehp480

PubMed ID:

19889649

Web of Science ID:

000273700600013

BORIS DOI:

10.7892/boris.37

URI:

https://boris.unibe.ch/id/eprint/37 (FactScience: 191633)

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