Growth hormone replacement therapy in adults with growth hormone deficiency improves vascular reactivity

Christ, E R; Chowienczyk, P J; Sönksen, P H; Russel-Jones, D L (1999). Growth hormone replacement therapy in adults with growth hormone deficiency improves vascular reactivity. Clinical endocrinology, 51(1), pp. 21-5. Oxford: Blackwell Scientific Publications 10.1046/j.1365-2265.1999.00805.x

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Patients with adult growth hormone (GH) deficiency are thought to be of increased risk of cardiovascular disease. Impaired vascular reactivity to endothelium derived nitric oxid (NO) is an early event in the development of atherosclerosis. In order to detect a possible effect of GH on vascular endothelium we examined forearm vasodilator responses in 8 patients with adult GH-deficiency before and after 3 months GH replacement therapy.

Item Type:

Journal Article (Original Article)

Division/Institute:

04 Faculty of Medicine > Department of Gynaecology, Paediatrics and Endocrinology (DFKE) > Clinic of Endocrinology, Diabetology and Clinical Nutrition

UniBE Contributor:

Christ, Emanuel

ISSN:

0300-0664

Publisher:

Blackwell Scientific Publications

Language:

English

Submitter:

Factscience Import

Date Deposited:

04 Oct 2013 15:23

Last Modified:

17 Mar 2015 22:49

Publisher DOI:

10.1046/j.1365-2265.1999.00805.x

PubMed ID:

10468961

Web of Science ID:

000081623400004

URI:

https://boris.unibe.ch/id/eprint/37234 (FactScience: 207246)

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