The use of stable isotopes to unravel the hyperlipidemia of adult growth hormone deficiency

Russell-Jones, D L; Christ, E; Cummings, M H; Umpleby, A M (1997). The use of stable isotopes to unravel the hyperlipidemia of adult growth hormone deficiency. Hormone research, 48 Suppl 5, pp. 111-115. Basel: Karger 10.1159/000191339

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Using stable isotope techniques to establish turnover rates for very low density lipoprotein (VLDL), a group of eight adult patients with growth hormone deficiency (GHD) exhibited an increased VLDL apoprotein B (apo B) secretion and decreased VLDL apoB metabolic clearance rate compared to controls. Such increased secretion is seen in some dyslipidemic states, including GHD, which are associated with atherosclerosis. The study of VLDL metabolism may provide a clue to the lipid metabolism disorder associated with GHD.

Item Type:

Journal Article (Original Article)

Division/Institute:

04 Faculty of Medicine > Department of Gynaecology, Paediatrics and Endocrinology (DFKE) > Clinic of Endocrinology, Diabetology and Clinical Nutrition

UniBE Contributor:

Christ, Emanuel

ISSN:

0301-0163

Publisher:

Karger

Language:

English

Submitter:

Factscience Import

Date Deposited:

04 Oct 2013 15:23

Last Modified:

05 Dec 2022 14:25

Publisher DOI:

10.1159/000191339

PubMed ID:

9434055

Web of Science ID:

000070940200018

URI:

https://boris.unibe.ch/id/eprint/37242 (FactScience: 207254)

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