Occurrence of Leishmania sp. in cutaneous lesions of horses in Central Europe

Müller, Norbert; Welle, Monika Maria; Lobsiger, Lisbeth; Stoffel, Michael Hubert; Kühni, Kathrin; Hilbe, Monika; Gottstein, Bruno; Frey, Caroline; Geyer, Claudia; von Bomhard, Wolf (2009). Occurrence of Leishmania sp. in cutaneous lesions of horses in Central Europe. Veterinary parasitology, 166(3-4), pp. 346-351. Amsterdam: Elsevier 10.1016/j.vetpar.2009.09.001

Text Müller_Leishmania in horses_2009_Vet Parasitol.pdf - Published Version Restricted to registered users only Available under License Publisher holds Copyright. Download (1MB) | Request a copy

The present report describes a novel etiological agent of cutaneous leishmaniasis in horses that, at least for some cases, sporadically appeared as autochthonous infections in geographically distant regions of Germany and Switzerland. The infection was initially diagnosed upon clinical and immunohistological findings. Subsequent comparative sequence analysis of diagnostic PCR products from the internal transcribed spacer 1 (ITS1) of ssrRNA classified the respective isolates as neither Old World nor New World Leishmania species. However, four isolates subjected to molecular analyses all exhibited a close phylogenetic relationship to Leishmania sp. siamensis, an organism recently identified in a visceral leishmaniasis patient from Thailand. Future investigations will demonstrate if this form of leishmaniasis represents an emerging, and perhaps zoonotic, disease of European, or even global, importance.

Interest & Impact

Downloads

1 since deposited on 04 Oct 2013
0 in the past 12 months

Citations

5 Citations in Web of Science ®
6 Citations in Scopus

Search

in Google Scholar™

Services

Actions (login required)

Edit item

Actions (login required)

Edit item