Graded doses of recombinant interleukin-1beta induce generalized osteopenia in rats without altering skeletal growth and joint integrity

del Pozo, E; Popp, A W E; MacKenzie, A; Perrelet, Romain; Lamberts, S W J; Lippuner, K (2005). Graded doses of recombinant interleukin-1beta induce generalized osteopenia in rats without altering skeletal growth and joint integrity. Hormone research, 64(2), pp. 88-95. Basel: Karger 10.1159/000088169

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Whereas a primary role of interleukin-1beta (IL-1beta) in local bone remodelling and articular inflammation has been well established, the effect of prolonged systemic administration of this cytokine on total skeletal Ca, somatic growth and joint tissue has not yet been investigated.

Item Type:

Journal Article (Original Article)

Division/Institute:

04 Faculty of Medicine > Department of Orthopaedic, Plastic and Hand Surgery (DOPH) > Clinic of Osteoporosis

UniBE Contributor:

Perrelet, Romain and Lippuner, Kurt

Subjects:

600 Technology > 610 Medicine & health

ISSN:

0301-0163

Publisher:

Karger

Language:

English

Submitter:

Factscience Import

Date Deposited:

04 Oct 2013 15:24

Last Modified:

12 Aug 2014 14:35

Publisher DOI:

10.1159/000088169

PubMed ID:

16155378

Web of Science ID:

000232489800006

URI:

https://boris.unibe.ch/id/eprint/37833 (FactScience: 211994)

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