[Fever of unknown origin as a sign of calcium pyrophosphate deposition disease]

Aeberli, D; Stanga, Z; Gerber, N J (2000). [Fever of unknown origin as a sign of calcium pyrophosphate deposition disease]. Schweizerische medizinische Wochenschrift, 130(14), pp. 505-9. Basel: B. Schwabe & Co.

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Calcium pyrophosphate dihydrate (CPPD) crystal deposition disease may manifest clinically as septic fever (40 degrees C), acute pseudogout attack of knee, wrist and shoulders, or as a variety of patterns of chronic inflammatory or degenerative joint disease. The association of pseudogout with fever is less widely recognised and may lead to over-investigation, delay in appropriate treatment and disproportionate costs. We report on a 67-year-old woman with a history of recurrent episodes of fever and polyarthritis every 2 months for the last 3 years. Because of this she was hospitalised several times, finally with suspected culture-negative endocarditis, and was treated for 6 weeks with gentamicin, rifampicin and vancomycin. During this therapy the patient again developed septic fever and acute arthritis of the right wrist. Radiographs of the wrist, knee and symphysis pubis revealed prominent chondrocalcinosis and destructive arthropathy.

Item Type:

Journal Article (Further Contribution)


04 Faculty of Medicine > Department of Gynaecology, Paediatrics and Endocrinology (DFKE) > Clinic of Endocrinology, Diabetology and Clinical Nutrition

UniBE Contributor:

Stanga, Zeno


600 Technology > 610 Medicine & health




B. Schwabe & Co.




Factscience Import

Date Deposited:

04 Oct 2013 15:24

Last Modified:

02 Mar 2023 23:23

PubMed ID:


Web of Science ID:



https://boris.unibe.ch/id/eprint/37917 (FactScience: 215101)

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