Hormographiella aspergillata keratomycosis in a dog

Rampazzo, A.; Kuhnert, P.; Howard, J.; Bornand, V. (2009). Hormographiella aspergillata keratomycosis in a dog. Veterinary ophthalmology, 12(1), pp. 43-7. Gainesville, Fla.: Blackwell Science 10.1111/j.1463-5224.2009.00672.x

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A 4-year-old, female, Border Collie was presented to the University of Bern Veterinary Teaching Hospital, because of a corneal lesion of 10 days duration. The axial cornea presented a whitish fluorescein-positive plaque with irregular margins. A diagnosis of keratomycosis was made based on cytology. Medical therapy with local broad-spectrum antibiotic and fluconazole was instituted. After 1 week of treatment, the improvement was deemed unsatisfactory. Therefore, a lamellar keratectomy and conjunctival pedicle flap were performed. After surgery, the cornea healed uneventfully. Histology confirmed the diagnosis of keratomycosis. The fungus could not be grown in culture and a precise etiological diagnosis could only be obtained with genetic identification of the fungus. A PCR technique was used to amplify the fungal genome from the cornea. Hormographiella aspergillata, the asexual reproductive form of the basidiomycete Coprinopsis cinerea, was identified. As advised in human medicine, we encourage the use of this molecular technique to obtain an early species diagnosis, allowing targeted medical therapy.

Item Type:

Journal Article (Original Article)

Division/Institute:

05 Veterinary Medicine > Department of Clinical Veterinary Medicine (DKV) > DKV - Central Clinical Laboratory
05 Veterinary Medicine > Department of Infectious Diseases and Pathobiology (DIP) > Institute of Veterinary Bacteriology

UniBE Contributor:

Kuhnert, Peter and Howard, Judith

ISSN:

1463-5216

Publisher:

Blackwell Science

Language:

English

Submitter:

Judith Howard

Date Deposited:

04 Oct 2013 15:24

Last Modified:

22 Jan 2015 09:43

Publisher DOI:

10.1111/j.1463-5224.2009.00672.x

Web of Science ID:

000262152000007

BORIS DOI:

10.7892/boris.38216

URI:

https://boris.unibe.ch/id/eprint/38216 (FactScience: 220734)

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