Cerebral extension of steroid-responsive meningitis arteritis in a boxer

Wrzosek, M.; Konar, M.; Vandevelde, M.; Oevermann, A. (2009). Cerebral extension of steroid-responsive meningitis arteritis in a boxer. Journal of small animal practice, 50(1), pp. 35-7. Oxford: Pergamon Press 10.1111/j.1748-5827.2008.00653.x

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A comatose 30-month-old, entire male boxer was presented because of an acute history of a cluster of three to four seizures. Neurological examination suggested a diffuse to multifocal intracranial lesion. Magnetic resonance tomography revealed symmetrical multifocal to diffuse changes of the cerebral grey matter and ependymal lining with sediment in the lateral ventricles. Haematological examination revealed leucocytosis with neutrophilia. Cerebrospinal fluid examination revealed high protein concentration and polymorphonuclear pleocytosis. Despite antiepileptic treatment, therapy against increased intracranial pressure and antibiosis, the dog's condition continued to deteriorate and he was euthanased. Pathological examination revealed fibrinosuppurative meningo-ependymitis and necrotising arteritis throughout the brain. In addition, chronic inflammation and arterial stenosis was found in the spinal meninges. No infectious agent was found. A diagnosis of steroid-responsive meningitis arteritis was made. The massive extension into the meninges and ventricular system of the forebrain has not been described previously in dogs with steroid-responsive meningitis arteritis and should be considered in the differential diagnosis when an intracranial suppurative infection is suspected.

Item Type:	Journal Article (Original Article)
Division/Institute:	05 Veterinary Medicine > Department of Clinical Veterinary Medicine (DKV) > DKV - Clinical Neurology 05 Veterinary Medicine > Department of Clinical Research and Veterinary Public Health (DCR-VPH) > Experimental Clinical Research
UniBE Contributor:	Vandevelde, Marc, Oevermann, Anna
ISSN:	0022-4510
Publisher:	Pergamon Press
Language:	English
Submitter:	Factscience Import
Date Deposited:	04 Oct 2013 15:25
Last Modified:	05 Dec 2022 14:26
Publisher DOI:	10.1111/j.1748-5827.2008.00653.x
Web of Science ID:	000262717500007
URI:	https://boris.unibe.ch/id/eprint/38262 (FactScience: 220782)