Mucosal lesions in a sheep infected with the Border Disease Virus (BDV)

Hilbe, M.; Camenisch, U.; Braun, U.; Peterhans, E.; Stalder, H.; Zlinszky, K.; Ehrensperger, F. (2009). Mucosal lesions in a sheep infected with the Border Disease Virus (BDV). Schweizer Archiv für Tierheilkunde, 151(8), pp. 391-6. Bern: Huber 10.1024/0036-7281.151.8.391

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A 28-week-old sheep was presented at the animal hospital because of chronic emaciation, anemia and slight diarrhea. Due to poor general condition and bad prognosis the animal was euthanized and submitted for postmortem investigation. Multiple erosions and ulcerations were found in the dorsal region of the tongue, the pharynx, the hard palate, in the esophagus and the ruminal pillars. Histologically, these lesions consisted of necrosuppurative inflammation. The animal was tested positive for pestivirus antigen both by immunohistochemical and by virological examination (cell culture, antigen capture ELISA and RT-PCR). A non-cytopathic Border Disease Virus was identified, and sequencing revealed a virus belonging to the BDV-3 cluster. Based on the macroscopical, histological, immunohistological and virological results this case was diagnosed as Border Disease with mucosal lesions. This is the first report of such a case in Switzerland.

Item Type:

Journal Article (Original Article)

Division/Institute:

05 Veterinary Medicine > Department of Infectious Diseases and Pathobiology (DIP) > Institute of Virology and Immunology

UniBE Contributor:

Peterhans, Ernst

ISSN:

0036-7281

Publisher:

Huber

Language:

English

Submitter:

Factscience Import

Date Deposited:

04 Oct 2013 15:25

Last Modified:

21 Jan 2014 15:05

Publisher DOI:

10.1024/0036-7281.151.8.391

Web of Science ID:

000269627500006

URI:

https://boris.unibe.ch/id/eprint/38309 (FactScience: 220992)

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