Mastitis-related subtypes of bovine Staphylococcus aureus are characterized by different clinical properties

Graber, H.U.; Naskova, J.; Studer, E.; Kaufmann, T.; Kirchhofer, M.; Brechbuhl, M.; Schaeren, W.; Steiner, A.; Fournier, C. (2009). Mastitis-related subtypes of bovine Staphylococcus aureus are characterized by different clinical properties. Journal of dairy science, 92(4), pp. 1442-51. Savoy, Ill.: American Dairy Science Association 10.3168/jds.2008-1430

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Based on a former study from our group, one subtype of Staphylococcus aureus was associated with high within-herd prevalence of mastitis, whereas the other subtypes were associated with a low prevalence (sporadic intramammary infection). To confirm this hypothesis, a prospective study was done in 29 Swiss dairy herds. In particular, milk samples were collected from 10 herds with Staph. aureus herd problems (cases) and compared with samples from 19 herds with only sporadic cases of with Staph. aureus intramammary infection (controls). The isolates were tested for their virulence gene pattern and genotyped by PCR amplification of the 16S-23S rRNA intergenic spacer. The patterns and genotypes were then associated and compared with epidemiological and clinical data. Confirming the hypothesis, one particular subtype (genotype B) was associated with high within-herd and within-cow prevalence of intramammary infection, whereas the other subtypes were associated with low within-herd prevalence and infected single quarters. The gene patterns and genotypes were highly related, demonstrating the genetic diversity of the genotypes. The somatic cell counts were clearly increased in herds with a genotype B problem compared with herds with infections of other genotypes. Based on the different clinical properties and treatment consequences associated with these different genotypes found in Switzerland, we recommend subtyping Staph. aureus in other countries to determine if this finding is universally applicable.

Item Type:

Journal Article (Original Article)

Division/Institute:

05 Veterinary Medicine > Department of Clinical Veterinary Medicine (DKV) > Clinic for Ruminants

UniBE Contributor:

Kaufmann, Thomas; Kirchhofer, Marc Peter and Steiner, Adrian

ISSN:

0022-0302

Publisher:

American Dairy Science Association

Language:

English

Submitter:

Factscience Import

Date Deposited:

04 Oct 2013 15:25

Last Modified:

17 Mar 2015 22:54

Publisher DOI:

10.3168/jds.2008-1430

Web of Science ID:

000264477700014

URI:

https://boris.unibe.ch/id/eprint/38410 (FactScience: 221364)

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