Traffic Routes and Signals for the Tonoplast

Pedrazzini, Emanuela; Komarova, Nataliya; Rentsch, Doris; Vitale, Alessandro (2013). Traffic Routes and Signals for the Tonoplast. Traffic, 14(6), pp. 622-628. Oxford: Wiley-Blackwell 10.1111/tra.12051

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Tonoplast, the membrane delimiting plant vacuoles, regulates ion, water and nutrient movement between the cytosol and the vacuolar lumen through the activity of its membrane proteins. Correct traffic of proteins from the endoplasmic reticulum (ER) to the tonoplast requires (i) approval by the ER quality control, (ii) motifs for exit from the ER and (iii) motifs that promote sorting to the tonoplast. Recent evidence suggests that this traffic follows different pathways that are protein-specific and could also reflect vacuole specialization for lytic or storage function. The routes can be distinguished based on their sensitivity to drugs such as brefeldin A and C834 as well as using mutant plants that are defective in adaptor proteins of vesicle coats, or dominant-negative mutants of Rab GTPases.

Item Type:

Journal Article (Original Article)

Division/Institute:

08 Faculty of Science > Department of Biology > Institute of Plant Sciences (IPS)
08 Faculty of Science > Department of Biology > Institute of Plant Sciences (IPS) > Molecular Plant Physiology

UniBE Contributor:

Komarova, Nataliya and Rentsch, Doris

Subjects:

500 Science > 580 Plants (Botany)

ISSN:

1398-9219

Publisher:

Wiley-Blackwell

Language:

English

Submitter:

Peter Alfred von Ballmoos-Haas

Date Deposited:

04 Dec 2013 13:28

Last Modified:

12 Jan 2015 21:21

Publisher DOI:

10.1111/tra.12051

Uncontrolled Keywords:

endoplasmic reticulum quality control; membrane proteins; plant-protein sorting; plant vacuole; storage vacuoles; tonoplast; vesicle traffic

BORIS DOI:

10.7892/boris.38693

URI:

https://boris.unibe.ch/id/eprint/38693

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