Lovric, Goran; Barré, Sébastien F.; Schittny, Johannes C.; Roth-Kleiner, Matthias; Stampanoni, Marco; Mokso, Rajmund (2013). Dose optimization approach to fast X-ray microtomography of the lung alveoli. Journal of applied crystallography, 46(Pt. 4), pp. 856-860. Blackwell 10.1107/S0021889813005591
Full text not available from this repository.A basic prerequisite for in vivo X-ray imaging of the lung is the exact determination of radiation dose. Achieving resolutions of the order of micrometres may become particularly challenging owing to increased dose, which in the worst case can be lethal for the imaged animal model. A framework for linking image quality to radiation dose in order to optimize experimental parameters with respect to dose reduction is presented. The approach may find application for current and future in vivo studies to facilitate proper experiment planning and radiation risk assessment on the one hand and exploit imaging capabilities on the other.
Item Type: |
Journal Article (Original Article) |
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Division/Institute: |
04 Faculty of Medicine > Pre-clinic Human Medicine > Institute of Anatomy 04 Faculty of Medicine > Pre-clinic Human Medicine > Institute of Anatomy > Functional Anatomy |
UniBE Contributor: |
Barré, Sébastien, Schittny, Johannes |
Subjects: |
600 Technology > 610 Medicine & health |
ISSN: |
0021-8898 |
Publisher: |
Blackwell |
Language: |
English |
Submitter: |
Johannes Schittny |
Date Deposited: |
10 Apr 2014 11:14 |
Last Modified: |
05 Dec 2022 14:26 |
Publisher DOI: |
10.1107/S0021889813005591 |
PubMed ID: |
24046488 |
Uncontrolled Keywords: |
X-ray microtomography, dose optimization, lung aveoli, radiation dose |
URI: |
https://boris.unibe.ch/id/eprint/38871 |