Temporary zinc oxide-eugenol cement: eugenol quantity in dentin and bond strength of resin composite

Koch, Tamara; Peutzfeldt, Anne; Malinovskii, Vladimir; Flury, Simon; Häner, Robert; Lussi, Adrian (2013). Temporary zinc oxide-eugenol cement: eugenol quantity in dentin and bond strength of resin composite. European journal of oral sciences, 121(4), pp. 363-369. Chichester: Wiley-Blackwell 10.1111/eos.12053

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Uptake of eugenol from eugenol-containing temporary materials may reduce the adhesion of subsequent resin-based restorations. This study investigated the effect of duration of exposure to zinc oxide–eugenol (ZOE) cement on the quantity of eugenol retained in dentin and on the microtensile bond strength (μTBS) of the resin composite. The ZOE cement (IRM Caps) was applied onto the dentin of human molars (21 per group) for 1, 7, or 28 d. One half of each molar was used to determine the quantity of eugenol (by spectrofluorimetry) and the other half was used for μTBS testing. The ZOE-exposed dentin was treated with either OptiBond FL using phosphoric acid (H3PO4) or with Gluma Classic using ethylenediaminetetraacetic acid (EDTA) conditioning. One group without conditioning (for eugenol quantity) and two groups not exposed to ZOE (for eugenol quantity and μTBS testing) served as controls. The quantity of eugenol ranged between 0.33 and 2.9 nmol mg−1 of dentin (median values). No effect of the duration of exposure to ZOE was found. Conditioning with H3PO4 or EDTA significantly reduced the quantity of eugenol in dentin. Nevertheless, for OptiBond FL, exposure to ZOE significantly decreased the μTBS, regardless of the duration of exposure. For Gluma Classic, the μTBS decreased after exposure to ZOE for 7 and 28 d. OptiBond FL yielded a significantly higher μTBS than did Gluma Classic. Thus, ZOE should be avoided in cavities later to be restored with resin-based materials.

Item Type:

Journal Article (Original Article)


04 Faculty of Medicine > School of Dental Medicine > Department of Preventive, Restorative and Pediatric Dentistry
08 Faculty of Science > Department of Chemistry, Biochemistry and Pharmaceutical Sciences (DCBP)

UniBE Contributor:

Koch, Tamara; Peutzfeldt, Anne; Flury, Simon; Häner, Robert and Lussi, Adrian


600 Technology > 610 Medicine & health
500 Science > 570 Life sciences; biology
500 Science > 540 Chemistry








Robert Häner

Date Deposited:

12 Dec 2013 16:08

Last Modified:

06 Dec 2014 21:56

Publisher DOI:


PubMed ID:


Uncontrolled Keywords:

adhesion, dentin bonding, IRM cement, temporary restoration





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