Antibodies to Aqx toxin of Actinobacillus equuli in horses and foals

Berthoud, H; Frey, Joachim; Sternberg, S; Straub, Reto; Kuhnert, Peter (2004). Antibodies to Aqx toxin of Actinobacillus equuli in horses and foals. Veterinary record, 155(8), pp. 231-233. London: British Veterinary Association 10.1136/vr.155.8.231

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Actinobacillus equuli is found in the normal oral flora of horses, but has been associated with several diseases, and particularly with the usually fatal septicaemia in neonatal foals which is thought to be associated with a failure of the passive transfer of immunoglobulins via the colostrum. The Aqx protein of A equuli, belonging to the RTX family of pore-forming toxins, is also cytotoxic to horse lymphocytes. The presence of antibodies to Aqx was investigated in sera from individual horses from different regions; the sera from adult horses and foals 24 hours after birth reacted with Aqx, and sera from foals sampled shortly after an intake of colostrum also reacted with Aqx, but sera from foals taken before an intake of colostrum did not react with Aqx.

Item Type:

Journal Article (Original Article)

Division/Institute:

05 Veterinary Medicine > Department of Infectious Diseases and Pathobiology (DIP) > Institute of Veterinary Bacteriology
05 Veterinary Medicine > Department of Clinical Veterinary Medicine (DKV) > Equine Clinic

UniBE Contributor:

Frey, Joachim; Straub, Reto and Kuhnert, Peter

Subjects:

500 Science
500 Science > 570 Life sciences; biology
600 Technology > 630 Agriculture

ISSN:

0042-4900

Publisher:

British Veterinary Association

Language:

English

Submitter:

Peter Kuhnert-Ryser

Date Deposited:

18 Dec 2013 11:21

Last Modified:

22 Dec 2014 09:51

Publisher DOI:

10.1136/vr.155.8.231

PubMed ID:

15384504

BORIS DOI:

10.7892/boris.39095

URI:

https://boris.unibe.ch/id/eprint/39095

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