Linking brain connectivity across different time scales with electroencephalogram, functional magnetic resonance imaging, and diffusion tensor imaging

Jann, Kay; Federspiel, Andrea; Giezendanner, Stéphanie; Andreotti, Jennifer; Kottlow, Mara; Dierks, Thomas; König, Thomas (2012). Linking brain connectivity across different time scales with electroencephalogram, functional magnetic resonance imaging, and diffusion tensor imaging. Brain connectivity, 2(1), pp. 11-20. Mary Ann Liebert 10.1089/brain.2011.0063

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Structural and functional connectivity are intrinsic properties of the human brain and represent the amount of cognitive capacities of individual subjects. These connections are modulated due to development, learning, and disease. Momentary adaptations in functional connectivity alter the structural connections, which in turn affect the functional connectivity. Thus, structural and functional connectivity interact on a broad timescale. In this study, we aimed to explore distinct measures of connectivity assessed by functional magnetic resonance imaging and diffusion tensor imaging and their association to the dominant electroencephalogram oscillatory property at rest: the individual alpha frequency (IAF). We found that in 21 healthy young subjects, small intraindividual temporal IAF fluctuations were correlated to increased blood oxygenation level-dependent signal in brain areas associated to working memory functions and to the modulation of attention. These areas colocalized with functionally connected networks supporting the respective functions. Furthermore, subjects with higher IAF show increased fractional anisotropy values in fascicles connecting the above-mentioned areas and networks. Hence, due to a multimodal approach a consistent functionally and structurally connected network related to IAF was observed.

Item Type:

Journal Article (Original Article)

Division/Institute:

04 Faculty of Medicine > University Psychiatric Services > University Hospital of Psychiatry and Psychotherapy > Psychiatric Neurophysiology (discontinued)

UniBE Contributor:

Jann, Kay; Federspiel, Andrea; Giezendanner, Stéphanie; Andreotti, Jennifer; Kottlow, Mara; Dierks, Thomas and König, Thomas

Subjects:

500 Science > 570 Life sciences; biology

ISSN:

2158-0014

Publisher:

Mary Ann Liebert

Language:

English

Submitter:

Thomas König

Date Deposited:

27 Jun 2014 08:21

Last Modified:

05 Dec 2014 03:29

Publisher DOI:

10.1089/brain.2011.0063

PubMed ID:

22574926

BORIS DOI:

10.7892/boris.39710

URI:

https://boris.unibe.ch/id/eprint/39710

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