Saito, Naomi; Kuginuki, Toshiaki; Yagyu, Takami; Kinoshita, Toshihiko; Koenig, Thomas; Pascual-Marqui, Roberto D.; Kochi, Kieko; Wackermann, Jiri; Lehmann, Dietrich (1998). Global, regional, and local measures of complexity of multichannel electroencephalography in acute, neuroleptic-naive, first-break schizophrenics. Biological psychiatry, 43(11), pp. 794-802. Elsevier 10.1016/S0006-3223(97)00547-7
![[img]](https://boris.unibe.ch/style/images/fileicons/text.png) |
Text
Schizo Omega.pdf - Published Version Restricted to registered users only Available under License Publisher holds Copyright. Download (96kB) |
Background: Schizophrenic symptoms commonly are felt to indicate a loosened coordination, i.e. a decreased connectivity of brain processes.
Methods: To address this hypothesis directly, global and regional multichannel electroencephalographic (EEG) complexities (omega complexity and dimensional complexity) and single channel EEG dimensional complexities were calculated from 19-channel EEG data from 9 neuroleptic-naive, first-break, acute schizophrenics and 9 age- and sex-matched controls. Twenty artifact-free 2 second EEG epochs during resting with closed eyes were analyzed (2–30 Hz bandpass, average reference for global and regional complexities, local EEG gradient time series for single channels).
Results: Anterior regional Omega-Complexity was significantly increased in schizophrenics compared with controls (p < 0.001) and anterior regional Dimensional Complexity showed a trend for increase. Single channel Dimensional Complexity of local gradient waveshapes was prominently increased in the schizophrenics at the right precentral location (p = 0.003).
Conclusions: The results indicate a loosened cooperativity or coordination (vice versa: an increased independence) of the active brain processes in the anterior brain regions of the schizophrenics.
Item Type: |
Journal Article (Original Article) |
|---|---|
Division/Institute: |
04 Faculty of Medicine > University Psychiatric Services > University Hospital of Psychiatry and Psychotherapy > Psychiatric Neurophysiology [discontinued] |
UniBE Contributor: |
König, Thomas |
Subjects: |
600 Technology > 610 Medicine & health |
ISSN: |
0006-3223 |
Publisher: |
Elsevier |
Language: |
English |
Submitter: |
Thomas König |
Date Deposited: |
18 Aug 2014 08:42 |
Last Modified: |
05 Dec 2022 14:27 |
Publisher DOI: |
10.1016/S0006-3223(97)00547-7 |
PubMed ID: |
9611668 |
Uncontrolled Keywords: |
global/regional omega complexity, global/regional dimensional complexity, correlation dimension, electroencephalographic gradients, multichannel electroencephalography, acute neuroleptic-naive schizophrenics |
BORIS DOI: |
10.7892/boris.39760 |
URI: |
https://boris.unibe.ch/id/eprint/39760 |
Actions (login required)
 |
Edit item |