Metabolic pathway and distribution of superparamagnetic iron oxide nanoparticles: in vivo study

Schlachter, Eva K; Widmer, Hans Ruedi; Bregy, Amadé; Lönnfors-Weitzel, Tarja; Vajtai, Istvan; Corazza, Nadia; Bernau, Vianney Jp; Weitzel, Thilo; Mordasini, Pasquale; Slotboom, Johannes; Herrmann, Gudrun; Bogni, Serge; Hofmann, Heinrich; Frenz, Martin; Reinert, Michael (2011). Metabolic pathway and distribution of superparamagnetic iron oxide nanoparticles: in vivo study. International journal of nanomedicine, 6, pp. 1793-1800. Auckland (NZ): DOVE Medical Press 10.2147/IJN.S23638

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Experimental tissue fusion benefits from the selective heating of superparamagnetic iron oxide nanoparticles (SPIONs) under high frequency irradiation. However, the metabolic pathways of SPIONs for tissue fusion remain unknown. Hence, the goal of this in vivo study was to analyze the distribution of SPIONs in different organs by means of magnetic resonance imaging (MRI) and histological analysis after a SPION-containing patch implantation.

Item Type:

Journal Article (Original Article)

Division/Institute:

04 Faculty of Medicine > Department of Head Organs and Neurology (DKNS) > Clinic of Neurosurgery
04 Faculty of Medicine > Department of Radiology, Neuroradiology and Nuclear Medicine (DRNN) > Institute of Diagnostic and Interventional Neuroradiology
04 Faculty of Medicine > Service Sector > Institute of Pathology
04 Faculty of Medicine > Pre-clinic Human Medicine > Institute of Anatomy
08 Faculty of Science > Institute of Applied Physics

UniBE Contributor:

Widmer, Hans Rudolf; Lönnfors-Weitzel, Tarja; Vajtai, Istvan; Corazza, Nadia; Mordasini, Pasquale; Slotboom, Johannes; Herrmann, Gudrun; Bogni, Serge; Frenz, Martin and Reinert, Michael

ISSN:

1176-9114

Publisher:

DOVE Medical Press

Language:

English

Submitter:

Factscience Import

Date Deposited:

04 Oct 2013 14:15

Last Modified:

08 Jun 2016 10:22

Publisher DOI:

10.2147/IJN.S23638

PubMed ID:

21980242

Web of Science ID:

000294280700001

URI:

https://boris.unibe.ch/id/eprint/4028 (FactScience: 208137)

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