Efficiency of risk-based vs . random sampling for the monitoring of tetracycline residues in slaughtered calves in Switzerland

Presi, Patrick; Stark, Katharina D. C.; Knopf, Lea; Breidenbach, Eric; Sanaa, Moez; Frey, Joachim; Regula, Gertraud (2008). Efficiency of risk-based vs . random sampling for the monitoring of tetracycline residues in slaughtered calves in Switzerland. Food additives & contaminants. Part A, Chemistry, analysis, control, exposure & risk assessment, 25(5), pp. 566-73. Taylor & Francis 10.1080/02652030701660544

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In all European Union countries, chemical residues are required to be routinely monitored in meat. Good farming and veterinary practice can prevent the contamination of meat with pharmaceutical substances, resulting in a low detection of drug residues through random sampling. An alternative approach is to target-monitor farms suspected of treating their animals with antimicrobials. The objective of this project was to assess, using a stochastic model, the efficiency of these two sampling strategies. The model integrated data on Swiss livestock as well as expert opinion and results from studies conducted in Switzerland. Risk-based sampling showed an increase in detection efficiency of up to 100% depending on the prevalence of contaminated herds. Sensitivity analysis of this model showed the importance of the accuracy of prior assumptions for conducting risk-based sampling. The resources gained by changing from random to risk-based sampling should be transferred to improving the quality of prior information.

Item Type:

Journal Article (Original Article)


05 Veterinary Medicine > Department of Clinical Research and Veterinary Public Health (DCR-VPH) > Veterinary Public Health Institute
05 Veterinary Medicine > Department of Infectious Diseases and Pathobiology (DIP) > Institute of Veterinary Bacteriology

UniBE Contributor:

Presi, Patrick; Frey, Joachim and Schüpbach, Gertraud


600 Technology > 630 Agriculture




Taylor & Francis




Gertraud Irene Regula

Date Deposited:

02 May 2014 17:18

Last Modified:

02 May 2014 17:18

Publisher DOI:


PubMed ID:




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