Visual complaints and visual hallucinations in Parkinson's disease

Urwyler, Prabitha; Nef, Tobias; Killen, Alison; Collerton, Daniel; Thomas, Alan; Burn, David; McKeith, Ian; Mosimann, Urs Peter (2014). Visual complaints and visual hallucinations in Parkinson's disease. Parkinsonism & related disorders, 20(3), pp. 318-322. Elsevier 10.1016/j.parkreldis.2013.12.009

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Background Visual symptoms are common in Parkinson's disease (PD) and are frequently under-diagnosed. The detection of visual symptoms is important for differential diagnosis and patient management. Aim To establish the prevalence of recurrent visual complaints (RVC) and recurrent visual hallucinations (RVH) and to investigate their interaction in PD patients and controls. Methods This cross-sectional study included 88 PD patients and 90 controls. RVC and RVH were assessed with a visual symptom questionnaire and the North-East-Visual-Hallucinations-Interview (NEVHI). Results Double vision (PD vs. Controls: 18.2% vs. 1.3%; p < 0.001), misjudging objects when walking (PD vs. Controls: 12.5% vs. 1.3%; p < 0.01), words moving whilst reading (PD vs. Controls: 17.0% vs. 1.3%; p < 0.001) and freezing in narrow spaces (PD vs. Controls: 30.7% vs. 0%; p < 0.001) were almost exclusively found in PD patients. The same was true for recurrent complex visual hallucinations and illusions (PD vs. Controls: both 17.0% vs. 0%; p < 0.001). Multiple RVC (43.2% vs. 15.8%) and multiple RVH (29.5% vs. 5.6%) were also more common in PD patients (both p < 0.001). RVC did not predict recurrent complex visual hallucinations; but double vision (p = 0.018, R2 = 0.302) and misjudging objects (p = 0.002, R2 = 0.302) predicted passage hallucinations. Misjudging objects also predicted the feeling of presence (p = 0.010, R2 = 0.321). Conclusions Multiple and recurrent visual symptoms are common in PD. RVC emerged as risk factors predictive of the minor forms of hallucinations, but not recurrent complex visual hallucinations.

Item Type:

Journal Article (Original Article)

Division/Institute:

04 Faculty of Medicine > University Psychiatric Services > University Hospital of Psychiatry and Psychotherapy
04 Faculty of Medicine > University Psychiatric Services > University Hospital of Geriatric Psychiatry and Psychotherapy
10 Strategic Research Centers > ARTORG Center for Biomedical Engineering Research > ARTORG Center - Gerontechnology and Rehabilitation

UniBE Contributor:

Urwyler-Harischandra, Prabitha; Nef, Tobias and Mosimann, Urs Peter

Subjects:

600 Technology > 610 Medicine & health

ISSN:

1353-8020

Publisher:

Elsevier

Language:

English

Submitter:

Pascal Wurtz

Date Deposited:

19 Feb 2014 08:45

Last Modified:

11 Nov 2015 09:56

Publisher DOI:

10.1016/j.parkreldis.2013.12.009

PubMed ID:

24405755

Uncontrolled Keywords:

Visual complaints, Visual hallucinations, Parkinson's disease

BORIS DOI:

10.7892/boris.40790

URI:

https://boris.unibe.ch/id/eprint/40790

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