Imaging Diagnosis - Lack of Contrast Enhancement in Metastatic Cerebral Adenocarcinoma

Brunner Singh, Jeannine; Oevermann, Anna; Henke, Diana; Ségard, Emilie; Gorgas, Daniela (2012). Imaging Diagnosis - Lack of Contrast Enhancement in Metastatic Cerebral Adenocarcinoma. Veterinary radiology & ultrasound, 53(2), pp. 193-196. Blackwell 10.1111/j.1740-8261.2011.01890.x

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A 7-year-old female spayed Scottish Terrier was presented with central nervous system symptoms suggestive of a lesion in the forebrain. Magnetic resonance (MR) imaging revealed multifocal disease in the forebrain. Because of complete lack of contrast enhancement, the changes were attributed to lesions of inflammatory origin.Histopathology of the brain revealed multiplemetastatic lesions of an adenocarcinoma. Brainmetastases in general show contrast enhancement. The reason for a complete absence of contrast enhancement is unknown. Previous administration of corticosteroids, increased diffusion time of contrast medium, increased intracranial pressure in combination with an intact blood–tumor barrier is discussed as possible reasons.

Item Type:

Journal Article (Original Article)

Division/Institute:

05 Veterinary Medicine > Department of Clinical Veterinary Medicine (DKV) > DKV - Clinical Radiology
05 Veterinary Medicine > Department of Clinical Veterinary Medicine (DKV)
05 Veterinary Medicine > Research Foci > NeuroCenter
05 Veterinary Medicine > Department of Clinical Veterinary Medicine (DKV) > DKV - Clinical Neurology
05 Veterinary Medicine > Department of Clinical Research and Veterinary Public Health (DCR-VPH) > Experimental Clinical Research
05 Veterinary Medicine > Department of Clinical Research and Veterinary Public Health (DCR-VPH)

UniBE Contributor:

Brunner Singh, Jeannine; Oevermann, Anna; Henke, Diana; Ségard, Emilie and Schweizer, Daniela Esther

Subjects:

600 Technology > 630 Agriculture

ISSN:

1058-8183

Publisher:

Blackwell

Language:

English

Submitter:

Christian Gutknecht

Date Deposited:

19 Feb 2014 14:29

Last Modified:

01 Nov 2017 12:03

Publisher DOI:

10.1111/j.1740-8261.2011.01890.x

BORIS DOI:

10.7892/boris.41901

URI:

https://boris.unibe.ch/id/eprint/41901

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